FK506 Binding Protein 5 (FKBP5) Peptide
FKBP5
Reactivity: Human
Host: Synthetic
BP, WB, IHC
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- Target See all FKBP5 products
- FKBP5 (FK506 Binding Protein 5 (FKBP5))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-FKBP5 antibody (Catalog #: ARP54713_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- FKBP5 (FK506 Binding Protein 5 (FKBP5))
- Synonyms
- FKBP5 Peptide, FKBP-5 Peptide, AIG6 Peptide, FKBP51 Peptide, FKBP54 Peptide, P54 Peptide, PPIase Peptide, Ptg-10 Peptide, D17Ertd592e Peptide, Dit1 Peptide, si:zc263a23.8 Peptide, wu:fc31g11 Peptide, wu:fl87b03 Peptide, zgc:64082 Peptide, FK506 binding protein 5 Peptide, FKBP5 Peptide, fkbp5 Peptide, Fkbp5 Peptide
- Background
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FKBP5 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. It is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FKBP51, FKBP54, MGC111006, P54, PPIase, Ptg-10, AIG6
Protein Interaction Partner: CHUK,CHUK,HSP90AA1,IKBKE,NR2C2,PGR,CDK9,ESR1,FES,HSF1,HSP90AA1,IKBKE,MAP3K1,PGR,PHLPP1,USP49
Protein Size: 457 - Molecular Weight
- 51 kDa
- Gene ID
- 2289
- NCBI Accession
- NM_004117, NP_004108
- UniProt
- Q13451
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