FK506 Binding Protein 5 (FKBP5) (N-Term) Peptide
FKBP5
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all FKBP5 products
- FKBP5 (FK506 Binding Protein 5 (FKBP5))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- SNGKKFDSSH DRNEPFVFSL GKGQVIKAWD IGVATMKKGE ICHLLCKPEY
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- FKBP5 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- FKBP5 (FK506 Binding Protein 5 (FKBP5))
- Synonyms
- FKBP5 Peptide, FKBP-5 Peptide, AIG6 Peptide, FKBP51 Peptide, FKBP54 Peptide, P54 Peptide, PPIase Peptide, Ptg-10 Peptide, D17Ertd592e Peptide, Dit1 Peptide, si:zc263a23.8 Peptide, wu:fc31g11 Peptide, wu:fl87b03 Peptide, zgc:64082 Peptide, FK506 binding protein 5 Peptide, FKBP5 Peptide, fkbp5 Peptide, Fkbp5 Peptide
- Background
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The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.
Alias Symbols: P54, AIG6, FKBP51, FKBP54, PPIase, Ptg-10
Protein Size: 457 - Gene ID
- 2289
- NCBI Accession
- NM_001145775, NP_001139247
- UniProt
- Q13451
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