Inositol Polyphosphate-5-Phosphatase, 75kDa (INPP5B) Peptide
INPP5B
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all INPP5B products
- INPP5B (Inositol Polyphosphate-5-Phosphatase, 75kDa (INPP5B))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-INPP5B antibody (Catalog #: ARP54772_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- INPP5B (Inositol Polyphosphate-5-Phosphatase, 75kDa (INPP5B))
- Synonyms
- 75kDa Peptide, AW260155 Peptide, INPP5P Peptide, 5PTase Peptide, inositol polyphosphate-5-phosphatase B Peptide, type II inositol 1,4,5-trisphosphate 5-phosphatase-like Peptide, inositol polyphosphate-5-phosphatase B L homeolog Peptide, inositol polyphosphate 5-phosphatase OCRL-1 Peptide, INPP5B Peptide, LOC100224437 Peptide, inpp5b.L Peptide, LOC100159919 Peptide, Inpp5b Peptide
- Background
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Cellular calcium signaling is controlled by the production of inositol phosphates (IPs) by phospholipase C in response to extracellular signals. The IP signaling molecules are inactivated by a family of inositol polyphosphate-5-phosphatases (5-phosphatases). INPP5B is the type II 5-phosphatase. The protein is localized to the cytosol and mitochondria, and associates with membranes through an isoprenyl modification near the C-terminus.Cellular calcium signaling is controlled by the production of inositol phosphates (IPs) by phospholipase C in response to extracellular signals. The IP signaling molecules are inactivated by a family of inositol polyphosphate-5-phosphatases (5-phosphatases). This gene encodes the type II 5-phosphatase. The protein is localized to the cytosol and mitochondria, and associates with membranes through an isoprenyl modification near the C-terminus. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
Alias Symbols: 5PTase, MGC65156, MGC71303
Protein Interaction Partner: SMURF1
Protein Size: 913 - Molecular Weight
- 77 kDa
- Gene ID
- 3633
- NCBI Accession
- NM_005540, NP_005531
- UniProt
- P32019
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