Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 4 (Psmd4) Peptide
Psmd4
Reactivity: Human
Host: Synthetic
BP, WB, IHC
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- Target See all PSMD4/ASF (Psmd4) products
- PSMD4/ASF (Psmd4) (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 4 (Psmd4))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PSMD4 antibody (Catalog #: ARP32341_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PSMD4/ASF (Psmd4) (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 4 (Psmd4))
- Synonyms
- af-1 Peptide, mcb1 Peptide, pub-r5 Peptide, rpn10 Peptide, PSMD4 Peptide, DDBDRAFT_0202512 Peptide, DDBDRAFT_0232981 Peptide, DDB_0202512 Peptide, DDB_0232981 Peptide, AF Peptide, AF-1 Peptide, ASF Peptide, MCB1 Peptide, Rpn10 Peptide, S5A Peptide, pUB-R5 Peptide, xrpn10c Peptide, Af1 Peptide, Mcb1 Peptide, angiocidin Peptide, im:6912672 Peptide, psmd4 Peptide, wu:fc68c04 Peptide, zgc:110247 Peptide, proteasome 26S subunit, non-ATPase 4 Peptide, 26S proteasome non-ATPase regulatory subunit 4 Peptide, 26s proteasome non-atpase regulatory subunit 4 (26s proteasomeregulatory subunit s5a) Peptide, proteasome 26S subunit, non-ATPase 4 L homeolog Peptide, proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 Peptide, proteasome 26S subunit, non-ATPase 4b Peptide, psmd4 Peptide, PSMD4 Peptide, LOC100194679 Peptide, psmD4 Peptide, LOC100283637 Peptide, Smp_000740.1 Peptide, psmd4.L Peptide, Psmd4 Peptide, psmd4b Peptide
- Background
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The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMD4 encodes one of the non-ATPase subunits of the 19S regulator lid.
Alias Symbols: AF, ASF, S5A, AF-1, MCB1, Rpn10, pUB-R5
Protein Interaction Partner: ID1,MYOD1,NEDD8,NUB1,RAD23A,RAD23B,RAD23B,RASSF8,STUB1,TCF3,UBB,UBB,UBQLN1,UBQLN2,ADRM1,NEDD8,NUB1,PAX3,PSMD10,PSMD13,PSMD14,PSMD6,PSMD7,RAD23A,RAD23B,RASSF8,Rad23a,Rad23b,UCHL5,USP14
Protein Size: 377 - Molecular Weight
- 41 kDa
- Gene ID
- 5710
- NCBI Accession
- NM_002810, NP_002801
- UniProt
- P55036
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