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Browse our CHUK (CHUK) ELISA Kits

Full name:
conserved Helix-Loop-Helix Ubiquitous Kinase ELISA Kits (CHUK)
On are 10 conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) ELISA Kits from 5 different suppliers available. Additionally we are shipping CHUK Antibodies (331) and CHUK Proteins (4) and many more products for this protein. A total of 358 CHUK products are currently listed.
AI256658, CHUK, Chuk1, Fbx24, Fbxo24, IKBKA, ikk, IKK-alpha, IKK1, Ikka, ikkalpha, NFKBIKA, TCF16, zgc:56539
list all ELISA KIts Gene Name GeneID UniProt
CHUK 1147 O15111
CHUK 12675  
CHUK 309361  

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More ELISA Kits for CHUK Interaction Partners

Human conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) interaction partners

  1. TRIM22 could interact with IkappaB kinase (IKK)alpha but not IKKbeta (show IKBKB ELISA Kits) and could increase the level and phosphorylation of IKKalpha through its really interesting new gene (RING) and spla-ryanodine receptor (show RYR3 ELISA Kits) (SPRY) domains.

  2. IKKalpha is diversely expressed in keratinizing and non-keratinizing carcinomas in the same type of cancer.

  3. results indicate that nuclear active IKK is a robust biomarker to predict cutaneous squamous cell carcinoma outcome, and suggest the possibility of targeting IKK activity as a future therapy for treating metastatic cutaneous squamous cell carcinomas

  4. BRAF (show BRAF ELISA Kits)-induced tumorigenesis is IKKalpha-dependent but NF-kappaB (show NFKB1 ELISA Kits)-independent

  5. We also report that the extra-genomic effects elicited by both ligands, leading to recruitment of active Akt (show AKT1 ELISA Kits) to chromatin, are essential for phosphorylation of serine 10 in histone H3 (show HIST3H3 ELISA Kits) by IKKa

  6. Upon infection, the HCV 3'UTR (show UTS2R ELISA Kits) redistributes DDX3X (show DDX3X ELISA Kits) and IKK-alpha to speckle-like cytoplasmic structures shown to be stress granules.

  7. Suppression of PKK (show RIPK4 ELISA Kits) expression by RNA interference inhibits phosphorylation of IKKalpha and IKKbeta (show IKBKB ELISA Kits) as well as activation of NF-kappaB (show NFKB1 ELISA Kits) in human cancer cell lines; thus, PKK (show RIPK4 ELISA Kits) regulates NF-kappaB (show NFKB1 ELISA Kits) activation by modulating activation of IKKalpha and IKKbeta (show IKBKB ELISA Kits).

  8. Silencing of IKKa in E2-challenged cells resulted into an increased presence of either 8-oxo-Gs as well as of the base excision repair enzyme 8-oxo-guanine-DNA glycosylase 1.

  9. Findings indicated that IKKalpha plays a crucial role as a tumor suppressor that suppresses the invasion, metastasis, and angiogenesis of nasopharyngeal carcinoma (NPC (show NPC1 ELISA Kits)) cells in vitro and correlates with the survival in NPC (show NPC1 ELISA Kits) patients.

  10. Authors show that activation of NF-kappaB (show NFKB1 ELISA Kits) by Kaposi's sarcoma-associated herpesvirus K15 (show KRT15 ELISA Kits) protein involves the recruitment of NF-kappaB (show NFKB1 ELISA Kits)-inducing kinase (NIK (show MAP3K14 ELISA Kits)) and IKK alpha/beta to result in the phosphorylation of p65/RelA (show NFkBP65 ELISA Kits) on Ser536.

Mouse (Murine) conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) interaction partners

  1. Hematopoietic IKKalpha deficiency in mouse suppresses Akt (show AKT1 ELISA Kits) signaling, compromising monocyte/macrophage survival and this decreases early atherosclerosis.

  2. Anatomy of a negative feedback loop: the case of IkappaBalpha (show NFKBIA ELISA Kits).

  3. Epithelial-intrinsic IKK-alpha expression regulates group 3 innate lymphoid cell responses and antibacterial immunity.

  4. IKKalpha mediated the repair of the kidney via infiltrated regulatory T (Treg) cells, which can produce anti-inflammatory cytokine IL10 (show IL10 ELISA Kits)

  5. phosphorylation of DBC1 (show DBC1 ELISA Kits) at its C terminus by IKKalpha facilitates its interaction with RelB (show RELB ELISA Kits) and IKKalpha, indicating that DBC1 (show DBC1 ELISA Kits)-mediated suppression of alternative NF-kappaB (show NFKB1 ELISA Kits) is regulated by IKKalpha.

  6. IKKalpha controls the inflammasome at the level of the adaptor molecule ASC (show STS ELISA Kits), which interacts with IKKalpha in the nucleus of resting macrophages in an IKKalpha kinase-dependent manner.

  7. Stimulated BTK (show BTK ELISA Kits)-deficient dendritic cells are defective in the induction of IKK alpha/beta phosphorylation and IRF-1 (show IRF1 ELISA Kits) activation.

  8. IKKalpha has a role in the maintenance of a normal Treg population and in the control of expansion of CD4 (show CD4 ELISA Kits) T cells

  9. TCR-stimulated activation of NF-kappaB requires the assembly of cytosolic p62-Bcl10-Malt1-IKK signalosomes, which may ensure highly regulated activation of NF-kappaB in response to TCR engagement.

  10. Data indicate a role of haematopoietic Ikkalpha kinase activation in the homeostasis of B-cells and regulatory T-cells.

Zebrafish conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) interaction partners

  1. These findings reveal a molecular mechanism regulating migration and invasion of epithelial cells and establish a key direct link between IKKbeta (show IKBKB ELISA Kits) and cell motility controlled by Rap (show LRPAP1 ELISA Kits)-integrin signaling.

  2. poky/chuk/ikk1 is required for differentiation of the zebrafish embryonic epidermis

  3. Ikk1 negatively regulates NF-kappaB (show NFKB1 ELISA Kits) by sequestering NEMO (show IKBKG ELISA Kits) from active IKK complexes, indicating that IKK1 can function as a repressor of NF-kappaB (show NFKB1 ELISA Kits).

CHUK Antigen Profile

Antigen Summary

This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor.

Alternative names and synonyms associated with CHUK

  • conserved helix-loop-helix ubiquitous kinase (chuk) Elisa Kit
  • conserved helix-loop-helix ubiquitous kinase (CHUK) Elisa Kit
  • conserved helix-loop-helix ubiquitous kinase (Chuk) Elisa Kit
  • AI256658 Elisa Kit
  • CHUK Elisa Kit
  • Chuk1 Elisa Kit
  • Fbx24 Elisa Kit
  • Fbxo24 Elisa Kit
  • IKBKA Elisa Kit
  • ikk Elisa Kit
  • IKK-alpha Elisa Kit
  • IKK1 Elisa Kit
  • Ikka Elisa Kit
  • ikkalpha Elisa Kit
  • NFKBIKA Elisa Kit
  • TCF16 Elisa Kit
  • zgc:56539 Elisa Kit

Protein level used designations for CHUK

IKK-A , IKK-alpha , NFKBIKA , i kappa-B kinase alpha , ikBKA , inhibitor of nuclear factor kappa-B kinase subunit alpha , nuclear factor NF-kappa-B inhibitor kinase alpha , SPFH domain-containing protein 1 , conserved helix-loop-helix ubiquitous kinase , I-kappa-B kinase 1 , I-kappa-B kinase-alpha , IKK-a kinase , IkB kinase alpha subunit , Nuclear factor NFkappaB inhibitor kinase alpha , TCF-16 , transcription factor 16 , I kappa B kinase 1 , I-kappa-B kinase alpha , IKK alpha , IkappaB kinase alpha , ikappaB kinase , IkB kinase-a , IKK1 , IKKa , pky

444556 Xenopus laevis
450673 Pan troglodytes
477796 Canis lupus familiaris
709511 Macaca mulatta
100174735 Pongo abelii
1147 Homo sapiens
12675 Mus musculus
309361 Rattus norvegicus
423669 Gallus gallus
100135662 Sus scrofa
281073 Bos taurus
393287 Danio rerio
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