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|Antigen||Cyclin A2 (CCNA2) Antibodies|
|Reactivity||Cow (Bovine), Human, Mouse (Murine) Alternatives|
|Conjugate||This Cyclin A antibody is un-conjugated Alternatives|
Immunocytochemistry (ICC), Western Blotting (WB)
|5 references available|
|Supplier||Log in to see|
Product Details anti-Cyclin A AntibodyTarget Details Cyclin A Application Details Handling References for anti-Cyclin A antibody (ABIN3043070) Images
|Purpose||Mouse IgG monoclonal antibody for Cyclin A, cyclin A2 (CCNA2) detection. Tested with WB, ICC in Human,bovine,mouse. No cross reactivity with other proteins.|
|Cross-Reactivity (Details)||No cross reactivity with other proteins.|
Mouse IgG monoclonal antibody for Cyclin A, cyclin A2 (CCNA2) detection. Tested with WB, ICC in Human,bovine,mouse.
Gene Name: cyclin A2
Protein Name: Cyclin-A2
|Immunogen||Recombinant bovine cyclin A.|
Target Details Cyclin AProduct Details anti-Cyclin A Antibody Application Details Handling References for anti-Cyclin A antibody (ABIN3043070) Images back to top
|Alternative Name||CCNA2 (CCNA2 Antibody Abstract)|
The mammalian A-type cyclin family consists of 2 members, cyclin A1(CCNA1) and cyclin A2(CCNA2). Human cyclin A gene is assigned to 4q26-q27. Cyclin A protein is synthesized and localized into the nucleus at the onset of S phase in nontransformed mammalian fibroblasts.
|Gene ID||890, 12428, 114494|
|Pathways||PI3K-Akt Signaling, Cell Division Cycle, AMPK Signaling, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA|
Application DetailsProduct Details anti-Cyclin A Antibody Target Details Cyclin A Handling References for anti-Cyclin A antibody (ABIN3043070) Images back to top
WB: Concentration: 0.5-1 μg/mL, Species: Human, bovine , mouse
ICC: Concentration: 1 μg/mL, Species: Human, bovine , mouse
Notes: Other applications have not been tested. Optimal dilutions should be determined by end users.
Antibody can be supported by chemiluminescence kit ABIN921123 in WB, supported by ABIN921230 in ICC.
|Restrictions||For Research Use only|
HandlingProduct Details anti-Cyclin A Antibody Target Details Cyclin A Application Details References for anti-Cyclin A antibody (ABIN3043070) Images back to top
|Reconstitution||Add 1 mL of PBS buffer will yield a concentration of 100 μg/mL.|
|Buffer||Mouse ascites fluid, 1.2 % sodium acetate, 2 mg BSA, with 0.01 mg Sodium azide as preservative.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
References for anti-Cyclin A antibody (ABIN3043070)Product Details anti-Cyclin A Antibody Target Details Cyclin A Application Details Handling Images back to top
|Product cited in:||
Zhao, Li, Gao, Wang, Yan, Zhan, Liu, Mao, Chen, Wang et al.: "Design, synthesis and biological evaluation of N-alkyl or aryl substituted isoindigo derivatives as potential dual cyclin-dependent kinase 2 (CDK2)/glycogen synthase kinase 3? (GSK-3?) ..." in: European journal of medicinal chemistry, Vol. 86, pp. 165-74, 2014
Li, Tian, Wang, Yao, Zhang, Lu, Sun, Gao, Xiao, Liu: "Down-regulation of miR-129-5p inhibits growth and induces apoptosis in laryngeal squamous cell carcinoma by targeting APC." in: PLoS ONE, Vol. 8, Issue 10, pp. e77829, 2013
Deng, Lu, Zhao, Sun, Shi, Fan, Liu, Zhou, Nie, Wu, Fan, Guo: "Ran GTPase protein promotes human pancreatic cancer proliferation by deregulating the expression of Survivin and cell cycle proteins." in: Biochemical and biophysical research communications, Vol. 440, Issue 2, pp. 322-9, 2013
Mao, Wang, Xiao, Xi, Sun, Zhang, Ye, Wan, Guo, Lei, Chen: "A role for LRIG1 in the regulation of malignant glioma aggressiveness." in: International journal of oncology, Vol. 42, Issue 3, pp. 1081-7, 2013
Lin, Fu, Zhao, Lin, Zou, Liu, Zhu, Wang, Yu: "Fbxw8 is involved in the proliferation of human choriocarcinoma JEG-3 cells." in: Molecular biology reports, Vol. 38, Issue 3, pp. 1741-7, 2011
ImagesProduct Details anti-Cyclin A Antibody Target Details Cyclin A Application Details Handling References for anti-Cyclin A antibody (ABIN3043070) back to top