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anti-Rabbit Cyclin D1 antibody for Western Blotting

Recommended Cyclin D1 Antibody (supplied by: Log in to see )

Antigen
Cyclin D1 (CCND1) Antibodies
  • AI327039
  • bcl-1
  • bcl1
  • BCL1
  • cb161
  • ccnd1
  • CCND1
  • ccnd1a
  • ccnd1b
  • ccndbp1
  • cD1
  • cycd1
  • CycD1
  • Cyl-1
  • d11s287e
  • D11S287E
  • etID37810.7
  • fb52e01
  • fc45c08
  • fc83a12
  • id:ibd1198
  • prad1
  • PRAD1
  • u21b31
  • U21B31
  • wu:fb52e01
  • wu:fc45c08
  • wu:fc83a12
  • ZHM
Epitope
N-Term
74
24
19
14
13
12
10
10
9
9
8
6
6
5
5
4
4
4
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Chicken, Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rabbit, Rat (Rattus), Xenopus laevis
363
130
120
15
13
12
10
9
8
3
3
2
2
1
1
1
1
Host
Rabbit
299
114
1
Clonality
Polyclonal
Conjugate
This Cyclin D1 antibody is un-conjugated
21
16
6
6
3
3
2
2
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
322
163
97
66
65
55
41
30
30
12
8
7
6
3
3
2
2
2
1
1
1
Supplier
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Catalog No. ABIN2777893
$ 289.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0011798571 ABIN927441 WB Rabbit N-Term Log in to see Polyclonal

Top referenced anti-Cyclin D1 antibody for Western Blotting

Similar anti-Cyclin D1 Antibodies

Application / Reactivity Human Dog (Canine) Mouse (Murine) Rabbit Rat (Rattus) Cow (Bovine) Chicken Xenopus laevis
Western Blotting (WB) 295 Antibodies 11 Antibodies 109 Antibodies 2 Antibodies 100 Antibodies 11 Antibodies 10 Antibodies 4 Antibodies
Proximity Ligation Assay (PLA) 1 Antibodies
Intracellular Staining (ICS) 1 Antibodies 1 Antibodies 1 Antibodies
Immunoprecipitation (IP) 1 Antibodies 66 Antibodies 24 Antibodies 24 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 65 Antibodies 20 Antibodies

General

Antigen Cyclin D1 (CCND1) Antibodies
Epitope N-Term
(74), (24), (19), (14), (13), (12), (10), (10), (9), (9), (8), (6), (6), (5), (5), (4), (4), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Chicken, Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rabbit, Rat (Rattus), Xenopus laevis
(363), (130), (120), (15), (13), (12), (10), (9), (8), (3), (3), (2), (2), (1), (1), (1), (1)
Host Rabbit
(299), (114), (1)
Clonality
Polyclonal
Conjugate This Cyclin D1 antibody is un-conjugated
(21), (16), (6), (6), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (IHC), Western Blotting (WB)
(322), (163), (97), (66), (65), (55), (41), (30), (30), (12), (8), (7), (6), (3), (3), (2), (2), (2), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-Cyclin D1 Antibody

Target Details Cyclin D1 Application Details Handling References for anti-Cyclin D1 Antibody (ABIN2777893) Images
Blocking Peptide Blocking peptide for this product available: ABIN974600
Sequence KCEEEVFPLA MNYLDRFLSL EPVKKSRLQL LGATCMFVAS KMKETIPLTA
Predicted Reactivity Bovine : 100 %, Human : 100 %, Pig : 100 %, Dog : 90 %, Guinea pig : 90 %, Mouse : 90 %, Rabbit : 90 %, Rat : 90 %, Chicken : 80 %, African clawed frog : 70 %
Characteristics This is a rabbit polyclonal antibody against CCND1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human CCND1

Target Details Cyclin D1

Product Details anti-Cyclin D1 Antibody Application Details Handling References for anti-Cyclin D1 Antibody (ABIN2777893) Images back to top
Antigen
Alternative Name CCND1 (CCND1 Antibody Abstract)
Background CCND1 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. CCND1 has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis. The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis.
Molecular Weight 34 kDa
Gene ID 595
NCBI Accession NM_053056, NP_444284
UniProt P24385
Pathways PI3K-Akt Signaling, Cell Division Cycle

Application Details

Product Details anti-Cyclin D1 Antibody Target Details Cyclin D1 Handling References for anti-Cyclin D1 Antibody (ABIN2777893) Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 295 AA

Restrictions For Research Use only

Handling

Product Details anti-Cyclin D1 Antibody Target Details Cyclin D1 Application Details References for anti-Cyclin D1 Antibody (ABIN2777893) Images back to top
Format Liquid
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage 4 °C,-20 °C
Storage Comment For short term use, store at 2-8 °C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-Cyclin D1 Antibody (ABIN2777893)

Product Details anti-Cyclin D1 Antibody Target Details Cyclin D1 Application Details Handling Images back to top
Background publications

Kibel, Jin, Klim, Luly, A Roehl, Wu, Suarez: "Association between polymorphisms in cell cycle genes and advanced prostate carcinoma." in: The Prostate, Vol. 68, Issue 11, pp. 1179-86, 2008

Images

Product Details anti-Cyclin D1 Antibody Target Details Cyclin D1 Application Details Handling References for anti-Cyclin D1 Antibody (ABIN2777893) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Cyclin D1 antibody (CCND1) (N-Term) (ABIN2777893) anti-Cyclin D1 (CCND1) (N-Term) antibody