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Browse our anti-Glycogen Synthase 1 (GYS1) Antibodies

Full name:
anti-Glycogen Synthase 1 (Muscle) Antibodies (GYS1)
On www.antibodies-online.com are 39 Glycogen Synthase 1 (Muscle) (GYS1) Antibodies from 11 different suppliers available. Additionally we are shipping Glycogen Synthase 1 Proteins (5) and Glycogen Synthase 1 Kits (1) and many more products for this protein. A total of 50 Glycogen Synthase 1 products are currently listed.
Synonyms:
GSY, GYS, GYS1, GYS2, Gys3, MGS, zgc:63701

Most Popular Reactivities for anti-Glycogen Synthase 1 (GYS1) Antibodies

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anti-Human Glycogen Synthase 1 Antibodies:

anti-Mouse (Murine) Glycogen Synthase 1 Antibodies:

anti-Rat (Rattus) Glycogen Synthase 1 Antibodies:

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Top referenced anti-Glycogen Synthase 1 Antibodies

  1. Human Monoclonal Glycogen Synthase 1 Primary Antibody for FACS, ELISA - ABIN969183 : Luttjeboer, Harada, Hughes, Johnson, Lilford, Mol: Tubal flushing for subfertility. in Cochrane database of systematic reviews (Online) 2007 (PubMed)

  2. Human Polyclonal Glycogen Synthase 1 Primary Antibody for IP, IHC - ABIN1043895 : Kelsall, Voss, Munro, Cuthbertson, Cohen: R3F, a novel membrane-associated glycogen targeting subunit of protein phosphatase 1 regulates glycogen synthase in astrocytoma cells in response to glucose and extracellular signals. in Journal of neurochemistry 2011 (PubMed)

More Antibodies against Glycogen Synthase 1 Interaction Partners

Pig (Porcine) Glycogen Synthase 1 (Muscle) (GYS1) interaction partners

  1. Expression analysis revealed that porcine GYS1 was highly expressed in the skeletal muscle and heart

Horse (Equine) Glycogen Synthase 1 (Muscle) (GYS1) interaction partners

  1. The GYS1 mutation was detected in 11 breeds; with prevalence of genetic susceptibility to Type 1 Polysaccharide Storage Myopathy varied from 0.5% to 62.4%.

  2. observed that the two miRNAs, namely, eca-miR (show MYLIP Antibodies)-33a and miR-17, inhibited LDHA (show LDHA Antibodies) and GYS1 expression via binding to the 3' UTR (show UTS2R Antibodies) sequences of each gene

  3. The tissue expression profiles of eGYS1, equine type II hexokinase (eHKII) and muscle-type phosphofructokinase (ePFKM) were determined by real-time PCR and western blot analysis.

  4. Study identified GYS1, encoding skeletal muscle glycogen synthase (GS), as a candidate gene for Polysaccharide storage myopathy; DNA sequence analysis revealed a mutation resulting in an Arg-to-his substitution in a highly conserved region of GS.

  5. The prevalence of a missense mutation of GYS1 in horses with polysaccharide storage myopathy and the prevalence of the mutation based on disease classification are reported.

  6. This GYS1 point mutation appears to cause a gain-of-function of the enzyme and to result in the accumulation of a glycogen-like, less-branched polysaccharide in skeletal muscle.

  7. The GYS1 mutation is an important cause of exertional rhabdomyolysis in UNited Kingdom horse breeds but does not account for all forms of polysaccharide storage myopathy.

Human Glycogen Synthase 1 (Muscle) (GYS1) interaction partners

  1. Overexpression of GYS1, MIF (show AMH Antibodies), and MYC (show MYC Antibodies) is associated with adverse outcome and poor response to azacitidine in myelodysplastic syndromes and acute myeloid leukemia (show BCL11A Antibodies)

  2. over-expression of muscle glycogen synthase (MGS)was detected in diabetic human kidney

  3. High glycogen synthase 1 expression is associated with myeloid leukemia (show BCL11A Antibodies).

  4. Data suggest that although COOH-terminal dephosphorylation is likely necessary for GS activation, protein kinase Akt-2- (Akt2 (show AKT2 Antibodies))-dependent NH2-terminal dephosphorylation is site for "fine-tuning" insulin (show INS Antibodies)-mediated GS activation in skeletal muscle.

  5. Allosteric regulation and the relationship between phosphorylation and the kinetics of glycogen synthase. [Review]

  6. The present findings demonstrate that physical inactivity-induced insulin (show INS Antibodies) resistance in muscle is associated with lower content/activity of key proteins in glucose transport/phosphorylation and storage.

  7. GYS1 regulation by HIF plays a central role in the hypoxic accumulation of glycogen, and hypoxia also upregulates the expression of UTP:glucose-1-phosphate urydylyltransferase (UGP2 (show UGP2 Antibodies)) and 1,4-alpha glucan branching enzyme (GBE1 (show GBE1 Antibodies))

  8. Exercise unmaskd the effect associated with the GYS1 polymorphism, rendering carriers of this allele less susceptible to the protective effect of exercise on the risk of cardiovascular mortality.

  9. the M416V polymorphism of glycogen synthase 1 gene is not associated with insulin (show INS Antibodies) resistance in type 2 diabetes

  10. Data show that myotubes defective in glycogen synthase (GS) activity express insulin (show INS Antibodies)-responsive glycogen synthase kinase-3alpha, suggesting that failure of insulin (show INS Antibodies) to decrease GS phosphorylation involves abnormal activity of another kinase or phosphatase.

Mouse (Murine) Glycogen Synthase 1 (Muscle) (GYS1) interaction partners

  1. We show that the absence of Epm2aip1 (show EPM2AIP1 Antibodies) in mice impairs allosteric activation of GS by glucose 6-phosphate, decreases hepatic glycogen synthesis, increases liver fat, causes hepatic insulin (show INS Antibodies) resistance, and protects against age-related obesity

  2. Muscle glycogen synthase isoform is responsible for testicular glycogen synthesis: glycogen overproduction induces apoptosis in male germ cells.

  3. Long-term potentiation (LTP (show SCP2 Antibodies)) evoked in the hippocampal CA3 (show CA3 Antibodies)-CA1 (show CA1 Antibodies) synapse was also decreased in behaving GYS1(Nestin (show NES Antibodies)-KO) mice.

  4. Neurodegeneration and functional impairments are associated with glycogen synthase accumulation in the mouse model of Lafora disease.

  5. GYS1 regulation by HIF plays a central role in the hypoxic accumulation of glycogen, and hypoxia also upregulates the expression of UTP:glucose-1-phosphate urydylyltransferase (UGP2 (show UGP2 Antibodies)) and 1,4-alpha glucan branching enzyme (GBE1 (show GBE1 Antibodies))

  6. Overexpression of glycogen synthase in skeletal muscle results in less branched glycogen.

  7. The endogenous glycogen synthase in extracts from mouse brain bound specifically to SAPK2b/p38b (show MAPK11 Antibodies) & was phosphorylated at residues Ser644, Ser652, Thr718 and Ser724.

  8. JNK signaling regulates the phosphorylation state of several kinases in skeletal muscle. JNK activation is unlikely to be the major mechanism by which contractile activity increases glycogen synthase activity in skeletal muscle.

  9. the GYS1 gene is not essential for strenuous exercise and has relatively little effect on endurance in mice

  10. In hearts from mPDK1 (show PDPK1 Antibodies)-/- or double GSK3alpha/GSK3beta (show GSK3b Antibodies) knockin mice, insulin (show INS Antibodies) failed to stimulate the activity of glycogen synthase or induce its dephosphorylation at residues that are phosphorylated by GSK3 (show GSK3b Antibodies).

Glycogen Synthase 1 (GYS1) Antigen Profile

Antigen Summary

The protein encoded by this gene catalyzes the addition of glucose monomers to the growing glycogen molecule through the formation of alpha-1,4-glycoside linkages. Mutations in this gene are associated with muscle glycogen storage disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Glycogen Synthase 1 (GYS1)

  • glycogen synthase 1 (muscle) (GYS1) antibody
  • glycogen synthase 1 (muscle) (gys1) antibody
  • glycogen synthase 1, muscle (Gys1) antibody
  • GSY antibody
  • GYS antibody
  • GYS1 antibody
  • GYS2 antibody
  • Gys3 antibody
  • MGS antibody
  • zgc:63701 antibody

Protein level used designations for GYS1

glycogen [starch] synthase, muscle , glycogen synthase 1 (muscle) , glycogen synthase 3, brain

GENE ID SPECIES
574064 Sus scrofa
456196 Pan troglodytes
394155 Danio rerio
378934 Gallus gallus
100054723 Equus caballus
100172871 Pongo abelii
511047 Bos taurus
611993 Canis lupus familiaris
2997 Homo sapiens
786335 Bos taurus
100008660 Oryctolagus cuniculus
574233 Macaca mulatta
14936 Mus musculus
690987 Rattus norvegicus
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