anti-Human Glycogen Synthase 1 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended Glycogen Synthase 1 Antibody (supplied by: Log in to see )

Antigen
Glycogen Synthase 1 (Muscle) (GYS1) Antibodies
  • GYS1
  • zgc:63701
  • GSY
  • GYS
  • GYS2
  • Gys3
  • MGS
  • glycogen synthase 1 (muscle)
  • glycogen synthase 1, muscle
  • GYS1
  • gys1
  • Gys1
Epitope
pSer641
6
5
4
2
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
40
21
17
4
4
4
Host
Rabbit
32
8
Clonality
Monoclonal
Application
Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
38
26
19
8
8
4
4
2
2
1
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Catalog No. ABIN5557475
$ 401.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN1734828 IHC (p) IP ELISA WB Rabbit IgG pSer640 Log in to see Polyclonal
1 ABIN742613 IF (p) IHC (p) WB Rabbit IgG pSer641 Log in to see Polyclonal
1 ABIN1714645 IF (p) IHC (p) WB Rabbit IgG pSer645 Log in to see Polyclonal
1 ABIN2767888 IP IHC (p) IHC ELISA WB Rabbit pSer640 Log in to see Polyclonal

General

Antigen Glycogen Synthase 1 (Muscle) (GYS1) Antibodies
Epitope pSer641
(6), (5), (4), (2), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(40), (21), (17), (4), (4), (4)
Host Rabbit
(32), (8)
Clonality (Clone)
Monoclonal   ( )
Application Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(38), (26), (19), (8), (8), (4), (4), (2), (2), (1)
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Product Details anti-Glycogen Synthase 1 Antibody

Target Details Glycogen Synthase 1 Application Details Handling Images
Purification Purified by Protein A.
Immunogen Synthetic peptide derived from human Glycogen synthase 1(S641), around 630-680aa (phospho S641).
Clone 10C1
Isotype IgG

Target Details Glycogen Synthase 1

Product Details anti-Glycogen Synthase 1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name Glycogen synthase 1 (GYS1 Antibody Abstract)
Background

Glycogen Synthase (GS) is a key enzyme in the regulation of glycogen metabolism. GS catalyzes the incorporation of UDP-glucose incorporation into glycogen. The activity of glycogen synthase is regulated by hormonal stimuli (insulin, catecholamines and glucagons) and non-hormonal stimuli (blood glucose level and exercise). Two main isoforms of mammalian GS are designated as muscle (glycogen synthase 1) and liver (glycogen synthase 2). Most tissues express glycogen synthase 1, whereas glycogen synthase 2 appears to be tissue-specific. The two isoforms have 70 % identical amino acid sequence. Glycogen synthase can be phosphorylated by multiple kinases including glycogen synthase kinase-3 (GSK-3), mitogen-activated protein kinase-related protein kinase (DYRK), and SAPK2b/p38b which leads to its inactivation.

Synonyms: Glycogen synthase 1 phospho S640, Glycogen synthase 1 phospho Ser640, p-Glycogen synthase 1 S640, Glycogen synthase 1 muscle, Glycogen synthase 1, GSY, GYS, GYS1, EC 2.4.1.11, Glycogen synthase1, GYS 1, Starchsynthase muscle, UDP glucose glycogen glucosyltransferase, GYS1_HUMAN, Glycogen [starch] synthase, muscl.

Gene ID 2997
UniProt P13807
Research Area Cancer, Metabolism
Pathways PI3K-Akt Signaling, AMPK Signaling, Cellular Glucan Metabolic Process

Application Details

Product Details anti-Glycogen Synthase 1 Antibody Target Details Glycogen Synthase 1 Handling Images back to top
Application Notes WB 1:1000-2000
IHC-P 1:50-200
IF(ICC) 1:50-200
Restrictions For Research Use only

Handling

Product Details anti-Glycogen Synthase 1 Antibody Target Details Glycogen Synthase 1 Application Details Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

Images

Product Details anti-Glycogen Synthase 1 Antibody Target Details Glycogen Synthase 1 Application Details Handling back to top
Supplier Images
Western Blotting (WB) image for anti-Glycogen Synthase 1 (Muscle) (GYS1) (pSer641) antibody (ABIN5557475) Lane 1: Aphidicolin treated Mouse liver lysates, Lane 2: Untreated Mouse Liver lysate...
Immunofluorescence (Cultured Cells) (IF (cc)) image for anti-Glycogen Synthase 1 (Muscle) (GYS1) (pSer641) antibody (ABIN5557475) A549 cells were stained with Glycogen synthase 1(S641) (10C1) Monoclonal Antibody at...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Glycogen Synthase 1 (Muscle) (GYS1) (pSer641) antibody (ABIN5557475) Paraformaldehyde-fixed, paraffin embedded mouse skeletal muscle, Antigen retrieval by...