anti-Dog (Canine) Hexokinase 2 antibody for Immunohistochemistry

Recommended Hexokinase 2 Antibody (supplied by: Log in to see )

Antigen
Hexokinase 2 (HK2) Antibodies
  • HK2
  • HKII
  • HXK2
  • hexokinase-2
  • AI642394
  • fi09d05
  • fi17h06
  • wu:fi09d05
  • wu:fi17h06
  • wu:fi31b04
  • zgc:55926
  • ARABIDOPSIS THALIANA HEXOKINASE 2
  • ATHXK2
  • F6F22.11
  • F6F22_11
  • HEXOKINASE 2
  • hexokinase 2
  • hexokinase 2
  • hexokinase-2-like
  • similar to D.occidentalis hexokinase HXK which is able to phosphorylate glucose and fructose; similar to S. cerevisiae HXK2 (YGL253W)
  • HK2
  • hk2
  • Hk2
  • HXK2
  • LOC100856448
Epitope
N-Term
32
30
17
7
5
5
4
4
4
3
3
3
2
2
1
1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus), Zebrafish
170
48
42
6
6
5
3
3
3
2
2
2
1
1
1
Host
Rabbit
121
62
Clonality
Polyclonal
Conjugate
This Hexokinase 2 antibody is un-conjugated
9
8
6
6
5
4
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
158
101
79
22
22
14
13
8
5
4
4
1
1
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Catalog No. ABIN2774067
$ 289.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
8.869368 ABIN2453132 FACS IF IHC WB Mouse IgG1 Log in to see 4C5
1 ABIN4317175 FACS ICC IF IHC IHC (p) WB Mouse IgG1 Log in to see 4C5

General

Antigen Hexokinase 2 (HK2) Antibodies
Epitope N-Term
(32), (30), (17), (7), (5), (5), (4), (4), (4), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus), Zebrafish
(170), (48), (42), (6), (6), (5), (3), (3), (3), (2), (2), (2), (1), (1), (1)
Host Rabbit
(121), (62)
Clonality
Polyclonal
Conjugate This Hexokinase 2 antibody is un-conjugated
(9), (8), (6), (6), (5), (4), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (IHC), Western Blotting (WB)
(158), (101), (79), (22), (22), (14), (13), (8), (5), (4), (4), (1), (1)
Pubmed 1 reference available
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Product Details anti-Hexokinase 2 Antibody

Target Details Hexokinase 2 Application Details Handling References for anti-Hexokinase 2 antibody (ABIN2774067) Images
Blocking Peptide Blocking peptide for this product available: ABIN978014
Sequence GTEHGEFLAL DLGGTNFRVL WVKVTDNGLQ KVEMENQIYA IPEDIMRGSG
Predicted Reactivity Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
Characteristics This is a rabbit polyclonal antibody against HK2. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human HK2

Target Details Hexokinase 2

Product Details anti-Hexokinase 2 Antibody Application Details Handling References for anti-Hexokinase 2 antibody (ABIN2774067) Images back to top
Antigen
Alternative Name HK2 (HK2 Antibody Abstract)
Background Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. HK2 (hexokinase 2) is the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this protein is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells. Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-348 AI278414.1 4-351 349-732 CB160837.1 11-394 c 733-1006 BM912287.1 1-274 c 1007-1333 AI085541.1 1-327 c 1334-1477 AW134604.1 8-151 1478-4058 AF148513.1 1-2581 4059-5498 BC064369.1 2575-4014 5499-5615 BM706373.1 303-419 5616-7109 BC064369.1 4130-5623
Alias Symbols: DKFZp686M1669, HKII, HXK2
Protein Interaction Partner: UBQLN1, MAGEA12, SUMO2, SUMO3, UBC, EGFR, rev, H2AFV, WDR61, ARIH2, PDLIM1, PYGL, NUBP1, IPO5, HEXB, FNTA, FBXO6, PARK2, UBD, ITGA4, NUDCD3, UBQLN4, SLC2A4, ELAVL1, PTGDS, ZBTB17, PRKCE, IGFBP4,
Protein Size: 917
Molecular Weight 102 kDa
Gene ID 3099
NCBI Accession NM_000189, NP_000180
UniProt P52789
Pathways PI3K-Akt Signaling, Carbohydrate Homeostasis

Application Details

Product Details anti-Hexokinase 2 Antibody Target Details Hexokinase 2 Handling References for anti-Hexokinase 2 antibody (ABIN2774067) Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 917 AA

Restrictions For Research Use only

Handling

Product Details anti-Hexokinase 2 Antibody Target Details Hexokinase 2 Application Details References for anti-Hexokinase 2 antibody (ABIN2774067) Images back to top
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-Hexokinase 2 antibody (ABIN2774067)

Product Details anti-Hexokinase 2 Antibody Target Details Hexokinase 2 Application Details Handling Images back to top
Background publications

Paudyal, Oriuchi, Paudyal, Higuchi, Nakajima, Endo: "Expression of glucose transporters and hexokinase II in cholangiocellular carcinoma compared using [18F]-2-fluro-2-deoxy-D-glucose positron emission tomography." in: Cancer science, Vol. 99, Issue 2, pp. 260-6, 2008

Images

Product Details anti-Hexokinase 2 Antibody Target Details Hexokinase 2 Application Details Handling References for anti-Hexokinase 2 antibody (ABIN2774067) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Hexokinase 2 (HK2) (N-Term) antibody (ABIN2774067) anti-Hexokinase 2 (HK2) (N-Term) antibody