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anti-Human MAPKAP1 antibody for Intracellular Flow Cytometry

Recommended MAPKAP1 Antibody (supplied by: Log in to see )

Antigen
Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1) Antibodies
  • AI591529
  • CG10105
  • D230039K05Rik
  • Dmel\\CG10105
  • dSin1
  • im:7143088
  • JC310
  • MAPKAP1
  • MGC53034
  • MIP1
  • mip1
  • si:ch73-242f23.1
  • sin1
  • SIN1
  • Sin1
  • sin1b
  • SIN1b
  • sin1g
  • SIN1g
Reactivity
Human
76
28
24
3
2
Host
Rabbit
79
Clonality
Polyclonal
Conjugate
This MAPKAP1 antibody is un-conjugated
2
2
2
2
2
2
Application
Intracellular Flow Cytometry (ICFC)
69
33
32
11
10
3
1
1
1
1
1
1
Supplier
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Catalog No. ABIN2665262
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008704084 ABIN2665261 ICFC Rabbit Log in to see Polyclonal

Top referenced anti-MAPKAP1 antibody for Intracellular Flow Cytometry

Similar anti-MAPKAP1 Antibodies

Application / Reactivity Human
ELISA 33 Antibodies
Flow Cytometry (FACS) 1 Antibodies
Immunocytochemistry (ICC) 2 Antibodies
Immunofluorescence (IF) 11 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 1 Antibodies
Immunohistochemistry (IHC) 33 Antibodies
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 12 Antibodies
Immunoprecipitation (IP) 4 Antibodies
Intracellular Flow Cytometry (ICFC) 2 Antibodies
Proximity Ligation Assay (PLA) 2 Antibodies
Western Blotting (WB) 67 Antibodies

General

Antigen Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1) Antibodies
Reactivity Human
(76), (28), (24), (3), (2)
Host Rabbit
(79)
Clonality (Clone)
Polyclonal   ( )
Conjugate This MAPKAP1 antibody is un-conjugated
(2), (2), (2), (2), (2), (2)
Application Intracellular Flow Cytometry (ICFC)
(69), (33), (32), (11), (10), (3), (1), (1), (1), (1), (1), (1)
Pubmed 3 references available
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Product Details anti-MAPKAP1 Antibody

Target Details MAPKAP1 Application Details Handling References for anti-MAPKAP1 Antibody (ABIN2665262) Images
Purification The antibody was purified by affinity chromatography.
Clone Poly6488

Target Details MAPKAP1

Product Details anti-MAPKAP1 Antibody Application Details Handling References for anti-MAPKAP1 Antibody (ABIN2665262) Images back to top
Antigen
Alternative Name MAPKAP1 (MAPKAP1 Antibody Abstract)
Background SIN1 encodes a protein that is highly similar to the yeast SIN1 protein, a stress-activated protein kinase. Recent studies have shown that it is identical to MIP1 for MEKK2 interacting protein 1. MAPKAP1 has also been shown to play a role in the TOR signaling process, a pathway that is involved in controlling cell growth and proliferation in response to environmental cues such as nutrients, growth factors and hormones. Within mTORC2, MAPKAP1 is required for complex formation and mTORC2 kinase activity. MAPKAP1 inhibits MAP3K2 by preventing its dimerization and autophosphorylation. It inhibits HRAS and KRAS signaling and enhances osmotic stress-induced phosphorylation of ATF2 and ATF2-mediated transcription. Multiple alternatively spliced isoforms of MAPKAP1 have been identified.
Pathways PI3K-Akt Signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-MAPKAP1 Antibody Target Details MAPKAP1 Handling References for anti-MAPKAP1 Antibody (ABIN2665262) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-MAPKAP1 Antibody Target Details MAPKAP1 Application Details References for anti-MAPKAP1 Antibody (ABIN2665262) Images back to top
Format Liquid
Concentration 0.5 mg/mL
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-MAPKAP1 Antibody (ABIN2665262)

Product Details anti-MAPKAP1 Antibody Target Details MAPKAP1 Application Details Handling Images back to top
Background publications

Wullschleger, Loewith, Hall: "TOR signaling in growth and metabolism." in: Cell, Vol. 124, Issue 3, pp. 471-84, 2006

Jacinto, Facchinetti, Liu, Soto, Wei, Jung, Huang, Qin, Su: "SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity." in: Cell, Vol. 127, Issue 1, pp. 125-37, 2006

Schroder, Bushell, Sculley: "The human stress-activated protein kinase-interacting 1 gene encodes JNK-binding proteins." in: Cellular signalling, Vol. 17, Issue 6, pp. 761-7, 2005

Images

Product Details anti-MAPKAP1 Antibody Target Details MAPKAP1 Application Details Handling References for anti-MAPKAP1 Antibody (ABIN2665262) back to top
Supplier Images
Western Blotting (WB) image for anti-MAPKAP1 antibody (Mitogen-Activated Protein Kinase Associated Protein 1) (ABIN2665262) anti-Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1) antibody