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anti-Human MAPKSP1 Antibodies:
anti-Mouse (Murine) MAPKSP1 Antibodies:
anti-Rat (Rattus) MAPKSP1 Antibodies:
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BCL2 (show BCL2 Antibodies) expression in mesennchymal lung cancer cells was induced by ERK1 (show MAPK3 Antibodies) activity through the upregulation of the MEK1 (show MAP2K1 Antibodies)/ERK1 (show MAPK3 Antibodies) scaffold protein (show HOMER1 Antibodies) MEK partner-1. Interfering with the MEK1 (show MAP2K1 Antibodies)/MP1 (show PITRM1 Antibodies)/ERK1 (show MAPK3 Antibodies) axis using a MEK1 (show MAP2K1 Antibodies) inhibitor or MP1 (show PITRM1 Antibodies) depletion repressed BCL2 (show BCL2 Antibodies) expression and sensitized MLCCs to chemoradiotherapy.
The present study was aimed at investigating whether the miR (show MLXIP Antibodies)-29c binding site single nucleotide polymorphisms within the 3'-UTRs of LAMTOR3 gene affected the gastric cancer risk.
we demonstrate that the MAPK (show MAPK1 Antibodies) scaffold protein (show HOMER1 Antibodies) MEK partner 1 (MP1) is important for gastrin (show GAST Antibodies)-induced phosphorylation of ERK1 (show MAPK3 Antibodies) and ERK2 (show MAPK1 Antibodies) and that MP1 (show PITRM1 Antibodies) promotes gastrin (show GAST Antibodies)-induced proliferation of AGS (show JAG1 Antibodies)-GR cells
identified polymorphisms in LAMTOR2 (show LAMTOR2 Antibodies) and LAMTOR3 do not seem to play a relevant role in breast cancer
A complex encoded by the MAPKSP1, ROBLD3 (show LAMTOR2 Antibodies), and c11orf59 (show LAMTOR1 Antibodies) genes interacts with the Rag GTPases, recruits them to lysosomes, and is essential for mTORC1 activation
We investigated the neuroprotective effect of glial-derived neurotrophic factor (GDNF) upon alcohol-exposed B92 cultures, as well as the role of the cytoskeleton and mitogen-activated protein kinase (show MAPK1 Antibodies) (MAPK (show MAPK1 Antibodies)) pathways in this effect.
This novel mechanism for localization of intracellular Leishmania amazonensis-mediated ERK1/2 phosphorylation required the endosomal scaffold protein MP1 and localized to Leishmania amazonensis parasitophorous vacuoles.
We show an essential function for late endosomes carrying the p14 (show PCOLCE Antibodies)-MP1 (LAMTOR2 (show LAMTOR2 Antibodies)/3) complex in focal adhesion dynamics.
Data indicate that LAMTOR3 protein is stabilized by associating with LAMTOR2 (show LAMTOR2 Antibodies).
A genome-wide RNAi screen in mouse embryonic stem cells identifies Mp1 as a key mediator of differentiation.
MP1 and the MP1*P14 (show PCOLCE Antibodies) complex have the potential to differentially modulate activating and inhibiting signals in the Raf (show RAF1 Antibodies)-MKK1 (show MAP2K1 Antibodies)/2-ERK1/2 (show MAPK1/3 Antibodies) pathway.
This gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 13.
MAPK scaffold protein 1
, mitogen-activated protein kinase kinase 1 interacting protein 1
, MEK binding partner 1
, late endosomal/lysosomal adaptor and MAPK and MTOR activator 3
, mitogen-activated protein kinase scaffold protein 1
, ragulator complex protein LAMTOR3
, MEK-binding partner 1
, mitogen activated protein, binding protein
, mitogen-activated protein kinase kinase 1-interacting protein 1
, MEK partner 1
, Mitogen-activated protein kinase kinase 1-interacting protein 1
, Mitogen-activated protein kinase scaffold protein 1
, putative mitogen-activated protein kinase kinase 1 interacting protein 1