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anti-Human PDK2 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended PDK2 Antibody (supplied by: Log in to see )

Antigen
Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) Antibodies
  • 3j828
  • MGC52849
  • MGC132353
  • Pdk
  • zgc:56209
  • PDK2
  • PDHK2
  • PDKII
  • pyruvate dehydrogenase kinase, isozyme 4
  • pyruvate dehydrogenase kinase, isoenzyme 2
  • pyruvate dehydrogenase kinase, isozyme 2
  • pdk4
  • pdk2
  • PDK2
  • Pdk2
Reactivity
Human
125
63
33
5
3
1
Host
Rabbit
104
41
Clonality
Polyclonal
Conjugate
This PDK2 antibody is un-conjugated
9
9
8
7
7
7
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
123
85
62
28
17
11
5
3
1
1
1
1
Supplier
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Catalog No. ABIN954072
$ 401.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
11.203815 ABIN4620476 EIA IHC (p) WB Rabbit Ig C-Term Log in to see Polyclonal 3
11.203815 ABIN4344598 ICC IF IHC IHC (p) WB Rabbit IgG Log in to see Polyclonal 1
11.203815 ABIN4890304 IHC IHC (p) WB Rabbit Log in to see Polyclonal
11.203815 ABIN4912898 IHC (p) WB Mouse IgG1 kappa Log in to see 180CT10-2-3
1 ABIN391037 IHC (p) WB Rabbit Ig AA 378-407, C-Term Log in to see Polyclonal 9
1 ABIN653784 FACS IHC (p) WB Rabbit Ig Log in to see Polyclonal 2
1 ABIN657996 IHC (p) WB Rabbit Ig AA 78-107, N-Term Log in to see Polyclonal
1 ABIN562160 IHC (p) RNAi ELISA WB Mouse IgG2a kappa AA 187-276, partial Log in to see 2G1 4
1 ABIN781865 EIA IHC (p) WB Mouse IgG2a Log in to see 2G1
1 ABIN781866 EIA IHC (p) WB Mouse IgG2a Log in to see 5F8
1 ABIN3044044 ICC IHC (p) WB Rabbit IgG AA 379-392, C-Term Log in to see Polyclonal
1 ABIN768724 IHC (p) WB Rabbit IgG Internal Region Log in to see Polyclonal
1 ABIN2626695 ICC IHC (p) WB Rabbit IgG AA 379-392 Log in to see Polyclonal
1 ABIN626054 IHC (p) ELISA WB Mouse IgG2a, kappa Log in to see 5F8
1 ABIN626053 IHC (p) ELISA WB Mouse IgG2a, kappa Log in to see 2G1
1 ABIN1723667 IHC (p) ELISA WB Mouse IgG2a kappa AA 187-276 Log in to see 5F8
1 ABIN1723666 IHC (p) ELISA WB Mouse IgG2a kappa AA 187-276 Log in to see 2G1
1 ABIN518756 IHC (p) ELISA WB Mouse IgG2a kappa AA 187-276, partial Log in to see 5F8
1 ABIN1841117 IHC (p) WB Rabbit C-Term Log in to see Polyclonal
1 ABIN751792 IHC (p) WB HRP Rabbit IgG Log in to see Polyclonal

Top referenced anti-PDK2 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-PDK2 Antibodies

Application / Reactivity Human
ELISA 74 Antibodies
Enzyme Immunoassay (EIA) 3 Antibodies
Flow Cytometry (FACS) 18 Antibodies
Immunochromatography (IC) 1 Antibodies
Immunocytochemistry (ICC) 4 Antibodies
Immunofluorescence (IF) 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 61 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 27 Antibodies
RNA Interference (RNAi) 1 Antibodies
Western Blotting (WB) 108 Antibodies

General

Antigen Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) Antibodies
Reactivity Human
(125), (63), (33), (5), (3), (1)
Host Rabbit
(104), (41)
Clonality
Polyclonal
Conjugate This PDK2 antibody is un-conjugated
(9), (9), (8), (7), (7), (7), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(123), (85), (62), (28), (17), (11), (5), (3), (1), (1), (1), (1)
Pubmed 4 references available
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Product Details anti-PDK2 Antibody

Target Details PDK2 Application Details Handling References for anti-PDK2 Antibody (ABIN954072) Images
Specificity This antibody recognizes Human PDK2.
Purification Protein A column, followed by protein affinity purification
Immunogen Recombinant Human PDK2 protein.
Isotype Ig

Target Details PDK2

Product Details anti-PDK2 Antibody Application Details Handling References for anti-PDK2 Antibody (ABIN954072) Images back to top
Antigen
Alternative Name PDK2 (PDK2 Antibody Abstract)
Background PDK2 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.Synonyms: Pyruvate dehydrogenase kinase isoform 2, Pyruvate dehydrogenase lipoamide kinase isozyme 2 mitochondrial
Molecular Weight 46154 Da
Gene ID 5164
NCBI Accession NP_001186828
Research Area Cancer, Metabolism
Pathways PI3K-Akt Signaling, RTK Signaling

Application Details

Product Details anti-PDK2 Antibody Target Details PDK2 Handling References for anti-PDK2 Antibody (ABIN954072) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-PDK2 Antibody Target Details PDK2 Application Details References for anti-PDK2 Antibody (ABIN954072) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-PDK2 Antibody (ABIN954072)

Product Details anti-PDK2 Antibody Target Details PDK2 Application Details Handling Images back to top
Background publications

Li, Kato, Chuang: "Pivotal role of the C-terminal DW-motif in mediating inhibition of pyruvate dehydrogenase kinase 2 by dichloroacetate." in: The Journal of biological chemistry, Vol. 284, Issue 49, pp. 34458-67, 2009

Fencl, Janda, Bláhová, Hríbal, Stekrová, Puchmajerová, Seeman: "Genotype-phenotype correlation in children with autosomal dominant polycystic kidney disease." in: Pediatric nephrology (Berlin, Germany), Vol. 24, Issue 5, pp. 983-9, 2009

Sun, Zhou, Chang, McFate, Verma, Califano: "Mitochondrial mutations contribute to HIF1alpha accumulation via increased reactive oxygen species and up-regulated pyruvate dehydrogenease kinase 2 in head and neck squamous cell carcinoma." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 15, Issue 2, pp. 476-84, 2009

Baker, Hetherington, Reeves, Müller, Aitken: "The rat sperm proteome characterized via IPG strip prefractionation and LC-MS/MS identification." in: Proteomics, Vol. 8, Issue 11, pp. 2312-21, 2008

Images

Product Details anti-PDK2 Antibody Target Details PDK2 Application Details Handling References for anti-PDK2 Antibody (ABIN954072) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-PDK2 antibody (Pyruvate Dehydrogenase Kinase, Isozyme 2) (ABIN954072) Flow cytometric analysis of Jurkat cells using PDK2 Antibody  (bottom histogram) comp...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-PDK2 antibody (Pyruvate Dehydrogenase Kinase, Isozyme 2) (ABIN954072) Immunohistochemistry analysis in formalin fixed and paraffin embedded skeletal muscle...
Western Blotting (WB) image for anti-PDK2 antibody (Pyruvate Dehydrogenase Kinase, Isozyme 2) (ABIN954072) Western blot analysis of PDK2 Antibody  in Jurkat cell line lysates (35ug/lane). PDK2...