PDK2 antibody (AA 128-407)

Catalog No. ABIN1681304

The Rabbit Polyclonal anti-PDK2 antibody is suitable to detect PDK2 in samples from Human. It has been validated for WB and IF.

Quick Overview for PDK2 antibody (AA 128-407) (ABIN1681304)

Target: PDK2 (Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDK2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-PDK2 Antibody

Binding Specificity: AA 128-407

Sequence: PTMAQGVLEY KDTYGDDPVS NQNIQYFLDR FYLSRISIRM LINQHTLIFD GSTNPAHPKH IGSIDPNCNV SEVVKDAYDM AKLLCDKYYM ASPDLEIQEI NAANSKQPIH MVYVPSHLYH MLFELFKNAM RATVESHESS LILPPIKVMV ALGEEDLSIK MSDRGGGVPL RKIERLFSYM YSTAPTPQPG TGGTPLAGFG YGLPISRLYA KYFQGDLQLF SMEGFGTDAV IYLKALSTDS VERLPVYNKS AWRHYQTIQE AGDWCVPSTE PKNTSTYRVS

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 128-407 of human PDK2 (NP_002602.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PDK2

Target: PDK2 (Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2))

Alternative Name: PDK2

Background: This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,PDK2,PDHK2,PDKII,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Warburg Effect,PDK2

Molecular Weight: 38 kDa/46 kDa

Gene ID: 5164

UniProt: Q15119

Pathways: PI3K-Akt Signaling, RTK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect