anti-Mouse (Murine) PDK2 antibody for Immunohistochemistry

Recommended PDK2 Antibody (supplied by: Log in to see )

Antigen
Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) Antibodies
  • 3j828
  • MGC52849
  • MGC132353
  • Pdk
  • zgc:56209
  • PDK2
  • PDHK2
  • PDKII
  • pyruvate dehydrogenase kinase, isozyme 4
  • pyruvate dehydrogenase kinase, isoenzyme 2
  • pyruvate dehydrogenase kinase, isozyme 2
  • pdk4
  • pdk2
  • PDK2
  • Pdk2
Epitope
Middle Region
18
14
11
10
10
8
5
3
3
3
2
2
2
2
2
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus), Zebrafish
127
79
44
12
4
1
1
1
1
1
1
1
Host
Rabbit
104
40
Clonality
Polyclonal
Conjugate
This PDK2 antibody is un-conjugated
9
9
8
7
7
7
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
125
86
64
31
20
13
5
3
1
1
1
1
1
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Catalog No. ABIN2777433
$ 289.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
9.438829 ABIN2426341 IHC ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN4344598 ICC IF IHC IHC (p) WB Rabbit IgG Log in to see Polyclonal 1
1 ABIN3186377 ELISA IHC WB Rabbit IgG Internal Region Log in to see Polyclonal
1 ABIN1860173 ICC IHC IP WB Rabbit IgG AA 155-379 Log in to see Polyclonal
1 ABIN2893800 IHC WB Rabbit Arg291 Log in to see Polyclonal
1 ABIN3198254 IHC WB Rabbit Log in to see Polyclonal
1 ABIN1922644 IHC ELISA WB Alkaline Phosphatase (AP) Rabbit IgG AA 378-407 Log in to see Polyclonal
1 ABIN1922645 IHC ELISA WB APC Rabbit IgG AA 378-407 Log in to see Polyclonal
1 ABIN1922646 IHC ELISA WB Biotin Rabbit IgG AA 378-407 Log in to see Polyclonal
1 ABIN1922650 IHC ELISA WB Alkaline Phosphatase (AP) Rabbit IgG AA 78-107 Log in to see Polyclonal
1 ABIN1922647 IHC ELISA WB FITC Rabbit IgG AA 378-407 Log in to see Polyclonal
1 ABIN1922649 IHC ELISA WB HRP Rabbit IgG AA 378-407 Log in to see Polyclonal
1 ABIN1922648 IHC ELISA WB PE Rabbit IgG AA 378-407 Log in to see Polyclonal
1 ABIN1922651 IHC ELISA WB APC Rabbit IgG AA 78-107 Log in to see Polyclonal
1 ABIN1922652 IHC ELISA WB Biotin Rabbit IgG AA 78-107 Log in to see Polyclonal
1 ABIN1922653 IHC ELISA WB FITC Rabbit IgG AA 78-107 Log in to see Polyclonal
1 ABIN1922655 IHC ELISA WB HRP Rabbit IgG AA 78-107 Log in to see Polyclonal
1 ABIN1922654 IHC ELISA WB PE Rabbit IgG AA 78-107 Log in to see Polyclonal
1 ABIN2583075 ELISA IHC WB Rabbit IgG AA 378-407 Log in to see Polyclonal
1 ABIN2583076 ELISA IHC WB Rabbit IgG AA 77-107 Log in to see Polyclonal

General

Antigen Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) Antibodies
Epitope Middle Region
(18), (14), (11), (10), (10), (8), (5), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Reactivity Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus), Zebrafish
(127), (79), (44), (12), (4), (1), (1), (1), (1), (1), (1), (1)
Host Rabbit
(104), (40)
Clonality
Polyclonal
Conjugate This PDK2 antibody is un-conjugated
(9), (9), (8), (7), (7), (7), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (IHC), Western Blotting (WB)
(125), (86), (64), (31), (20), (13), (5), (3), (1), (1), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-PDK2 Antibody

Target Details PDK2 Application Details Handling References for anti-PDK2 antibody (ABIN2777433) Images
Blocking Peptide Blocking peptide for this product available: ABIN981539
Sequence ELFKNAMRAT VESHESSLIL PPIKVMVALG EEDLSIKMSD RGGGVPLRKI
Predicted Reactivity Cow: 77%, Dog: 92%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 92%, Zebrafish: 77%
Characteristics This is a rabbit polyclonal antibody against PDK2. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human PDK2

Target Details PDK2

Product Details anti-PDK2 Antibody Application Details Handling References for anti-PDK2 antibody (ABIN2777433) Images back to top
Antigen
Alternative Name PDK2 (PDK2 Antibody Abstract)
Background PDK2 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.
Alias Symbols: PDHK2
Protein Interaction Partner: VSIG4, DLAT, ISOC2, HIC2, SGK1, PDK2, PDK1, PDHA1, PDHX, AKT1, HTT,
Protein Size: 407
Molecular Weight 44 kDa
Gene ID 5164
NCBI Accession NM_002611, NP_002602
UniProt Q15119
Research Area Cancer, Metabolism
Pathways PI3K-Akt Signaling, RTK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process

Application Details

Product Details anti-PDK2 Antibody Target Details PDK2 Handling References for anti-PDK2 antibody (ABIN2777433) Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 407 AA

Restrictions For Research Use only

Handling

Product Details anti-PDK2 Antibody Target Details PDK2 Application Details References for anti-PDK2 antibody (ABIN2777433) Images back to top
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-PDK2 antibody (ABIN2777433)

Product Details anti-PDK2 Antibody Target Details PDK2 Application Details Handling Images back to top
Background publications

Hiromasa, Yan, Roche: "Specific ion influences on self-association of pyruvate dehydrogenase kinase isoform 2 (PDHK2), binding of PDHK2 to the L2 lipoyl domain, and effects of the lipoyl group-binding site inhibitor, Nov3r." in: Biochemistry, Vol. 47, Issue 8, pp. 2312-24, 2008

Images

Product Details anti-PDK2 Antibody Target Details PDK2 Application Details Handling References for anti-PDK2 antibody (ABIN2777433) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) (Middle Region) antibody (ABIN2777433) anti-Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) (Middle Region) antibody