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|Antigen||6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2) Antibodies|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This PFKFB2 antibody is conjugated to Alexa Fluor 350 Alternatives|
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
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Product Details anti-PFKFB2 AntibodyTarget Details PFKFB2 Application Details Handling Images
|Purification||Purified by Protein A.|
|Immunogen||KLH conjugated synthetic peptide derived from human PFKFB2|
Target Details PFKFB2Product Details anti-PFKFB2 Antibody Application Details Handling Images back to top
|Alternative Name||Pfkfb2 (PFKFB2 Antibody Abstract)|
PFKFB2 is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. It has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. PFKFB2 regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. There are two named isoforms.
Synonyms: 6 phosphofructo 2 kinase/fructose 2 6 biphosphatase 2, 6-bisphosphatase, 6-P2ase 2, 6-P2ASE heart-type isozyme, 6PF 2 K/Fru 2 6 P2ASE heart type isozyme, 6PF-2-K/Fru-2, F262_HUMAN, Fructose 2 6 bisphosphatase cardiac isozyme, Fructose-2, PFK 2/FBPase 2, PFK/FBPase 2, PFKFB cardiac, PFKFB2.
|Research Area||Cancer, Metabolism|
|Pathways||PI3K-Akt Signaling, Positive Regulation of Peptide Hormone Secretion, Regulation of Carbohydrate Metabolic Process|
Application DetailsProduct Details anti-PFKFB2 Antibody Target Details PFKFB2 Handling Images back to top
|Application Notes||IF(IHC-P) 1:50-200|
|Restrictions||For Research Use only|
HandlingProduct Details anti-PFKFB2 Antibody Target Details PFKFB2 Application Details Images back to top
|Buffer||Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.|
|Storage Comment||Store at 4°C|
|Expiry Date||12 months|