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anti-Mouse (Murine) PIK3CA antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended PIK3CA Antibody (supplied by: Log in to see )

Antigen
Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) Antibodies
  • 6330412C24Rik
  • C-P3K
  • caPI3K
  • CLOVE
  • CWS5
  • MCAP
  • MCM
  • MCMTC
  • p110
  • p110-alpha
  • p110alpha
  • pi3-k
  • PI3-kinase
  • PI3K
  • pi3k
  • PI3K-alpha
Reactivity
Human, Mouse (Murine)
141
47
42
7
4
2
1
1
1
Host
Rabbit
99
23
22
Clonality
Polyclonal
Conjugate
This PIK3CA antibody is un-conjugated
6
6
6
6
5
5
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
87
74
67
28
11
11
8
5
5
3
2
2
1
1
Supplier
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Catalog No. ABIN498480
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008935586 ABIN375147 EIA IHC (p) Goat Internal Region Log in to see Polyclonal 1
0.0008935586 ABIN372794 EIA IHC (p) Goat IgG Internal Region Log in to see Polyclonal
0.0008935586 ABIN677198 IF (p) IHC (p) WB Rabbit IgG AA 1010-1050 Log in to see Polyclonal 1
0.0008935586 ABIN2854758 IHC (p) WB Rabbit IgG N-Term Log in to see Polyclonal
0.0008935586 ABIN1804114 IHC (p) WB Rabbit IgG Log in to see Polyclonal
0.0008935586 ABIN677200 IHC (p) WB Biotin Rabbit IgG AA 1010-1050 Log in to see Polyclonal
0.0008935586 ABIN677207 IHC (p) WB HRP Rabbit IgG AA 1010-1050 Log in to see Polyclonal
0.0008935586 ABIN1738100 IHC (p) ELISA Goat Internal Region Log in to see Polyclonal
0.0008935586 ABIN2476129 IHC (p) ELISA Goat IgG Internal Region, Subunit alpha Log in to see Polyclonal
0.0008935586 ABIN2963809 IHC (p) WB Rabbit IgG Log in to see Polyclonal
0.0008935586 ABIN2792818 IHC (p) WB Rabbit IgG Log in to see Polyclonal

Top referenced anti-PIK3CA antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-PIK3CA Antibodies

Application / Reactivity Mouse (Murine) Human
BioImaging (BI) 2 Antibodies 2 Antibodies
ELISA 8 Antibodies 68 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies 5 Antibodies
Flow Cytometry (FACS) 2 Antibodies 11 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies 11 Antibodies
Immunohistochemistry (IHC) 17 Antibodies 75 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 12 Antibodies
Immunoprecipitation (IP) 4 Antibodies
Western Blotting (WB) 30 Antibodies
ELISA (Capture) 1 Antibodies
Immunocytochemistry (ICC) 3 Antibodies
Immunofluorescence (IF) 6 Antibodies

General

Antigen Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) Antibodies
Reactivity Human, Mouse (Murine)
(141), (47), (42), (7), (4), (2), (1), (1), (1)
Host Rabbit
(99), (23), (22)
Clonality
Polyclonal
Conjugate This PIK3CA antibody is un-conjugated
(6), (6), (6), (6), (5), (5), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(87), (74), (67), (28), (11), (11), (8), (5), (5), (3), (2), (2), (1), (1)
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Product Details anti-PIK3CA Antibody

Target Details PIK3CA Application Details Handling Images
Specificity This antibody detects endogenous levels of PI 3-kinase p110alpha protein. (region surrounding Arg519)
Cross-Reactivity (Details) Species reactivity (tested):Human, Mouse.
Purification Affinity chromatography
Purity > 95 % by SDS-PAGE

Target Details PIK3CA

Product Details anti-PIK3CA Antibody Application Details Handling Images back to top
Antigen
Alternative Name PIK3CA (PIK3CA Antibody Abstract)
Background Phosphatidylinositol 3-kinase (PI 3-kinase) is composed of 85 kDa (p85) and 110 kDa (p110) subunits. p85 lacks PI 3-kinase activity and acts as an adapter, coupling p110 to activated protein tyrosine kinase. Two forms of p85 have been described (p85alpha and p85beta), each possessing one SH3 and two SH2 domains. Various p110 isoforms have been identified. p110alpha and p110beta interact with p85alpha, and p110alpha has also been shown to interact with p85beta in vitro. p110delta expression is restricted to white blood cells. It has been shown to bind p85alpha and beta, but it apparently does not phosphorylate these subunits. p110delta seems to have the capacity to autophosphorylate. p110gamma does not interact with the p85 subunits. It has been shown to be activated by alpha and beta-gamma heterotrimeric G proteins.Synonyms: 5-bisphosphate 3-kinase catalytic subunit alpha isoform, EC=2.7.1.153, PI3-kinase p110 subunit alpha, PI3K, PIK3CA, Phosphatidylinositol-4, PtdIns-3-kinase p110
Molecular Weight approx. 110 kDa
Gene ID 5290
NCBI Accession NP_006209
UniProt P42336
Pathways PI3K-Akt Signaling, RTK Signaling, AMPK Signaling, Interferon-gamma Pathway, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-PIK3CA Antibody Target Details PIK3CA Handling Images back to top
Application Notes Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-PIK3CA Antibody Target Details PIK3CA Application Details Images back to top
Concentration 1,0 mg/mL
Buffer Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Images

Product Details anti-PIK3CA Antibody Target Details PIK3CA Application Details Handling back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-PIK3CA antibody (Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide) (ABIN498480) Immunohistochemistry (IHC) analyzes of PI 3-kinase p110alpha antibody in paraf...
Western Blotting (WB) image for anti-PIK3CA antibody (Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide) (ABIN498480) Western blot (WB) analysis of PI3-Kinase p110alpha antibody in extra...