Browse our anti-PITRM1 (PITRM1) Antibodies

Full name:
anti-Pitrilysin Metallopeptidase 1 Antibodies (PITRM1)
On www.antibodies-online.com are 56 Pitrilysin Metallopeptidase 1 (PITRM1) Antibodies from 16 different suppliers available. Additionally we are shipping PITRM1 Proteins (9) and and many more products for this protein. A total of 71 PITRM1 products are currently listed.
Synonyms:
2310012C15Rik, AA410010, MAP2K1IP1, MAPBP, MAPKSP1, mKIAA1104, MP-1, MP1, Ntup1, PITRM1, PreP, PRO0633, Ragulator3, wu:fa03d09, zgc:55469
list all antibodies Gene Name GeneID UniProt
PITRM1 8649 Q9UHA4
PITRM1 69617 Q8K411
PITRM1 307081  

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Most Popular Reactivities for anti-PITRM1 (PITRM1) Antibodies

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anti-Human PITRM1 Antibodies:

anti-Mouse (Murine) PITRM1 Antibodies:

anti-Rat (Rattus) PITRM1 Antibodies:

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Top referenced anti-PITRM1 Antibodies

  1. Human Polyclonal PITRM1 Primary Antibody for EIA, WB - ABIN954153 : Pinho, Björk, Alikhani, Bäckman, Eneqvist, Fratiglioni, Glaser, Graff: Genetic and biochemical studies of SNPs of the mitochondrial A beta-degrading protease, hPreP. in Neuroscience letters 2010 (PubMed)
    Show all 5 references for 954153

More Antibodies against PITRM1 Interaction Partners

Mouse (Murine) Pitrilysin Metallopeptidase 1 (PITRM1) interaction partners

  1. results suggest that pitrilysin regulates islet amyloid polypeptide (show IAPP Antibodies) in beta cells and suggest the presence of an intramitochondrial pool of islet amyloid polypeptide (show IAPP Antibodies) involved in beta-cell apoptosis.

  2. Pitrm1 is expressed in Pax3 (show PAX3 Antibodies)-expressing myoblast progenitors in the limb, the dermomyotome, and developing muscles of the face and torso.

Human Pitrilysin Metallopeptidase 1 (PITRM1) interaction partners

  1. The authors identified two siblings carrying a homozygous PITRM1 missense mutation (c.548G>A, p.Arg183Gln) associated with an autosomal recessive, slowly progressive syndrome characterised by mental retardation, spinocerebellar ataxia, cognitive decline and psychosis.

  2. Data show that the hPreP presequence only targets GFP to the matrix of mammalian and yeast mitochondria.

  3. This study demonstrated decreased proteolytic activity of the mitochondrial amyloid-beta degrading enzyme, PreP peptidasome, in Alzheimer's disease brain mitochondria.

  4. our data suggest that genetic variation in the hPreP gene PITRM1 may potentially contribute to mitochondrial dysfunctions

  5. The substrate specificity of the mitochondrial metallopeptidase proteinase 1 (MP1) was investigated and its mitochondrial targeting signal identified.

  6. Data revealed that six polymorphisms of F10 (show F10 Antibodies), PITRM1, PCSK2 (show PCSK2 Antibodies), JPH3 (show JPH3 Antibodies), MYO7B (show MYO7B Antibodies), and AKAP12 (show AKAP12 Antibodies) were related (P<0.05) to the prevalence of chronic kidney disease.

PITRM1 Antigen Profile

Antigen Summary

ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides. Specific for peptides in the range of 10 to 65 residues. Able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion, suggesting a link with Alzheimer disease. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference.

Alternative names and synonyms associated with PITRM1

  • late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 (LAMTOR3) antibody
  • pitrilysin metallopeptidase 1 (PITRM1) antibody
  • pitrilysin metallepetidase 1 (Pitrm1) antibody
  • pitrilysin metallopeptidase 1 (Pitrm1) antibody
  • DKFZP468C1910 protein (DKFZP468C1910) antibody
  • pitrilysin metallopeptidase 1 (pitrm1) antibody
  • pitrilysin metalloproteinase 1 (pitrm1) antibody
  • 2310012C15Rik antibody
  • AA410010 antibody
  • MAP2K1IP1 antibody
  • MAPBP antibody
  • MAPKSP1 antibody
  • mKIAA1104 antibody
  • MP-1 antibody
  • MP1 antibody
  • Ntup1 antibody
  • PITRM1 antibody
  • PreP antibody
  • PRO0633 antibody
  • Ragulator3 antibody
  • wu:fa03d09 antibody
  • zgc:55469 antibody

Protein level used designations for PITRM1

MAPK scaffold protein 1 , MEK binding partner 1 , late endosomal/lysosomal adaptor and MAPK and MTOR activator 3 , mitogen-activated protein kinase kinase 1 interacting protein 1 , mitogen-activated protein kinase scaffold protein 1 , ragulator complex protein LAMTOR3 , PreP peptidasome , metalloprotease 1 (pitrilysin family) , pitrilysin metalloproteinase 1 , presequence protease, mitochondrial , nuclear transplantation upregulated protein 1 , pitrilysin metalloprotease 1 , pitrilysin metallepetidase 1 , Pitrilysin metalloproteinase 1

GENE ID SPECIES
8649 Homo sapiens
10531 Homo sapiens
69617 Mus musculus
307081 Rattus norvegicus
100189669 Pongo abelii
379672 Xenopus laevis
406808 Danio rerio
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