|Application / Reactivity||Human||Mouse (Murine)||Cow (Bovine)||Rat (Rattus)|
|Western Blotting (WB)||39 Antibodies||9 Antibodies||1 Antibodies||8 Antibodies|
|Proximity Ligation Assay (PLA)||1 Antibodies|
|Immunoprecipitation (IP)||8 Antibodies||1 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||3 Antibodies||3 Antibodies||3 Antibodies|
|Immunohistochemistry (IHC)||3 Antibodies||2 Antibodies||2 Antibodies|
|Immunofluorescence (Paraffin-embedded Sections) (IF (p))||11 Antibodies||11 Antibodies||11 Antibodies|
|Antigen||Protein Phosphatase 2, Regulatory Subunit B', gamma (PPP2CA) Antibodies|
|Epitope||AA 53-66 Alternatives|
|Reactivity||Cow (Bovine), Human, Mouse (Murine), Rat (Rattus) Alternatives|
Western Blotting (WB)
|1 reference available|
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|Specificity||This antibody reacts to Protein phosphatase 2A (PP2A).|
|Immunogen||Antibody raised against synthetic peptide corresponding to amino acids 53 to 66 of the mammalian protein phosphatase 2 A/B conjugated to KLH.|
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|Alternative Name||PPP2R5C (PPP2CA Antibody Abstract)|
|Background||Protein phosphatase 2A (PP2A) is a hetertrimeric enzyme consisting of a catalytic subunits (C), a structural subunit (A) and a variable regulatory subunit (B). The B subunit family is made up of the a, b and g isoforms. The PP2A/Bg isoform appears to only be detectable in the brain where it has been speculated that it cytoskeletal substrates. The RNA which produces the PP2A/Bg is developmentally regulated and increases sharply after birth. It has also been suggested that it may be important in the establishment and maintenance of neuronal connections.Synonyms: KIAA0044, NY-REN-29, PP2A B subunit B' gamma isoform, PP2A B subunit B56 gamma isoform, PP2A B subunit PR61 gamma isoform, PP2A B subunit R5 gamma isoform, Protein phosphatase 2A, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform|
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Western Blot: Detects a 56 kDa band. Positive Control: Whole rat brain homogenate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
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|Buffer||Phosphate buffered saline with 0.08 % sodium azide|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage Comment||The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.|
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Strack, Zaucha, Ebner et al.: "Brain protein phosphatase 2A: developmental regulation and distinct cellular and subcellular localization by B subunits." in: The Journal of comparative neurology, Vol. 392, Issue 4, pp. 515-27, 1998 (PubMed).
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