PPP2R5C antibody (Regulatory Subunit Gamma)

Catalog No. ABIN7169258

Product Details anti-PPP2R5C Antibody

Target: PPP2R5C (Protein Phosphatase 2, Regulatory Subunit B', gamma (PPP2R5C))

Binding Specificity: AA 1-320, Regulatory Subunit Gamma

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP2R5C antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform protein (1-320AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PPP2R5C

Target: PPP2R5C (Protein Phosphatase 2, Regulatory Subunit B', gamma (PPP2R5C))

Alternative Name: PPP2R5C (PPP2R5C Products)

Synonyms: B56G antibody, PR61G antibody, 2610043M05Rik antibody, 2700063L20Rik antibody, AI060890 antibody, AW545884 antibody, C85228 antibody, D12Bwg0916e antibody, mKIAA0044 antibody, b56g antibody, ppp2r5c antibody, si:dkey-241l7.9 antibody, protein phosphatase 2 regulatory subunit B'gamma antibody, protein phosphatase 2, regulatory subunit B', gamma antibody, protein phosphatase 2 regulatory subunit B', gamma antibody, protein phosphatase 2, regulatory subunit B', gamma b antibody, protein phosphatase 2, regulatory subunit B', gamma a antibody, PPP2R5C antibody, Ppp2r5c antibody, ppp2r5c antibody, ppp2r5c.L antibody, ppp2r5cb antibody, ppp2r5ca antibody

Background:

Background: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. The PP2A-PPP2R5C holoenzyme may specifically dephosphorylate and activate TP53 and play a role in DNA damage-induced inhibition of cell proliferation. PP2A-PPP2R5C may also regulate the ERK signaling pathway through ERK dephosphorylation.

Aliases: 2A5G_HUMAN antibody, B' alpha regulatory subunit antibody, B56G antibody, KIAA0044 antibody, MGC23064 antibody, PP2A B subunit B' gamma isoform antibody, PP2A B subunit B56 gamma isoform antibody, PP2A B subunit isoform B' gamma antibody, PP2A B subunit isoform B''-gamma antibody, PP2A B subunit isoform B56-gamma antibody, PP2A B subunit isoform PR61-gamma antibody, PP2A B subunit isoform R5-gamma antibody, PP2A B subunit PR61 gamma isoform antibody, PP2A B subunit R5 gamma isoform antibody, Ppp2r5c antibody, PR61G antibody, Protein phosphatase 2 regulatory subunit B (B56) gamma isoform antibody, Protein phosphatase 2 regulatory subunit B' gamma antibody, Protein phosphatase 2, regulatory subunit B', gamma isoform antibody, Renal carcinoma antigen NY REN 29 antibody, Renal carcinoma antigen NY-REN-29 antibody, Serine/threonine protein phosphatase 2A 56 kDa regulatory subunit gamma isoform antibody, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform antibody

UniProt: Q13362

Pathways: PI3K-Akt Signaling