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|Antigen||Protein Phosphatase 2, Regulatory Subunit B', delta (PPP2R5D) Antibodies|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This PPP2R5D antibody is conjugated to Alexa Fluor 594 Alternatives|
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
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Product Details anti-PPP2R5D AntibodyTarget Details PPP2R5D Application Details Handling Images
|Purification||Purified by Protein A.|
|Immunogen||KLH conjugated synthetic peptide derived from human PPP2R5D|
Target Details PPP2R5DProduct Details anti-PPP2R5D Antibody Application Details Handling Images back to top
|Alternative Name||PPP2R5D (PPP2R5D Antibody Abstract)|
In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit, and a catalytic subunit. Four major families of protein phosphatase catalytic subunits have been identified, designated PP1, PP2A, PP2B (calcineurin) and PP2C. An additional protein phosphatase catalytic subunit, PPX (also known as PP4) is a putative member of a novel PP family. The PP2A family comprises subfamily members PP2A Alpha and PP2A Beta. The PP2A catalytic subunit associates with a variety of regulatory subunits. Regulatory subunits include PP2A-A-Alpha and -A-Beta, PP2A-B-Alpha and -B-Beta, PP2A-C-Alpha and -C-Beta, PP2A-B56-Alpha, -B56-Beta, -B56-gamma and -B56-Delta.
Synonyms: B'delta, Delta isoform of regulatory subunit B56, protein phosphatase 2A, MGC2134, MGC8949, OTTHUMP00000039821, PP2A B subunit B' delta isoform, PP2A B subunit B56 delta isoform, PP2A B subunit PR61 delta isoform, PP2A B subunit R5 delta isoform, Protein phosphatase 2 regulatory subunit B B56 delta isoform, Protein phosphatase 2 regulatory subunit B delta isoform, Serine threonine protein phosphatase 2A 56 kDa regulatory subunit delta isoform, TEG-271, Tex271, 2A5D_HUMAN.
|Pathways||PI3K-Akt Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades|
Application DetailsProduct Details anti-PPP2R5D Antibody Target Details PPP2R5D Handling Images back to top
|Application Notes||IF(IHC-P) 1:50-200|
|Restrictions||For Research Use only|
HandlingProduct Details anti-PPP2R5D Antibody Target Details PPP2R5D Application Details Images back to top
|Buffer||Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Storage Comment||Store at 4°C|
|Expiry Date||12 months|