PPP2R5D antibody (Catalytic Subunit)

Catalog No. ABIN306653

Product Details anti-PPP2R5D Antibody

Target: PPP2R5D (Protein Phosphatase 2, Regulatory Subunit B', delta (PPP2R5D))

Binding Specificity: Catalytic Subunit

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP2R5D antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Cross-Reactivity: Cow, Human, Mouse, Rat

Characteristics: pp2A/Bd, rabbit anti protein phosphatase 2A, B subunit delta, PP2A B subunit delta,A protein phosphatase is a phosphatase enzyme that removes a phosphate group from the phosphorylated amino acid residue of its substrate protein. Protein phosphorylation is one of the most common forms of reversible protein posttranslational modification (PTM), with up to 30 % of all proteins being phosphorylated at any given time. Protein kinases (PKs) are the effectors of phosphorylation and catalyse the transfer of a γ-phosphate from ATP to specific amino acids on proteins. Several hundred PKs exist in mammals and are classified into distinct super-families. Proteins are phosphorylated predominantly on Ser, Thr and Tyr residues, which account for 79.3, 16.9 and 3.8 % respectively of the phosphoproteome, at least in mammals. In contrast, protein phosphatases (PPs) are the primary effectors of dephosphorylation and can be grouped into three main classes based on sequence, structure and catalytic function. The largest class of PPs is the phosphoprotein phosphatase (PPP) family comprising PP1, PP2A, PP2B, PP4, PP5, PP6 and PP7, and the protein phosphatase Mg²- or Mn²-dependent (PPM) family, composed primarily of PP2C.

Purification: Ammonium Sulfate Precipitation

Immunogen: The immunogen used to generate the purified antibody was a peptide conjugated to KLH corresponding to the sequence NH2-Cys-Ala-Val-Pro-Asp-Ser-Glu-Arg-Val-IlePro-Pro-Arg-Thr-Thr-Thr-Pro-Tyr-COOH. This peptide antibody corresponds to C -terminal peptide of PPV catalytic subunit having a MW of 33kDa.

Isotype: IgG

Application Details

Application Notes: Applications: Immunoblotting 1-10 μg/mL and 10-20 μg/mL for Immunoprecipitation.

Restrictions: For Research Use only

Handling

Buffer: Provided as solution in phosphate buffered saline with 0.08 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Target Details for PPP2R5D

Target: PPP2R5D (Protein Phosphatase 2, Regulatory Subunit B', delta (PPP2R5D))

Alternative Name: Protein Phosphatase 2 A/B delta (PPP2R5D Products)

Synonyms: B56D antibody, B'delta antibody, TEG-271 antibody, Tex271 antibody, zgc:73160 antibody, zgc:77529 antibody, ppp2r5d antibody, MDS026 antibody, protein phosphatase 2 regulatory subunit B'delta antibody, protein phosphatase 2, regulatory subunit B', delta antibody, serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform antibody, protein phosphatase 2 regulatory subunit Bdelta antibody, PPP2R5D antibody, Ppp2r5d antibody, ppp2r5d antibody, LOC100176996 antibody, PPP2R2D antibody

Pathways: PI3K-Akt Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades