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Browse our RPS6KB2 Proteins (RPS6KB2)

Full name:
Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 2 Proteins (RPS6KB2)
On www.antibodies-online.com are 11 Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 2 (RPS6KB2) Proteins from 8 different suppliers available. Additionally we are shipping RPS6KB2 Antibodies (219) and RPS6KB2 Kits (5) and many more products for this protein. A total of 245 RPS6KB2 products are currently listed.
Synonyms:
70kDa, KLS, p70(S6K)-beta, P70-beta, P70-beta-1, P70-beta-2, p70S6Kb, S6K-beta2, S6K2, SRK, STK14B
list all proteins Gene Name GeneID UniProt
RPS6KB2 6199 Q9UBS0
Rat RPS6KB2 RPS6KB2 361696  
RPS6KB2 58988 Q9Z1M4

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RPS6KB2 Proteins (RPS6KB2) by Origin

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More Proteins for RPS6KB2 Interaction Partners

Human Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 2 (RPS6KB2) interaction partners

  1. discovered that ERBB4 (show ERBB4 Proteins) and S6K2 were the direct targets of miR (show MLXIP Proteins)-193a-3p and that PIK3R3 and mTOR (show FRAP1 Proteins) were the direct targets of miR (show MLXIP Proteins)-193a-5p in non-small-cell lung cancer

  2. Degradation of Tiam1 (show TIAM1 Proteins) by casein kinase 1 (show CSNK1A1 Proteins) and the SCFbetaTrCP ubiquitin ligase controls the duration of mTOR (show FRAP1 Proteins)-S6K (show RPS6KB1 Proteins) signaling.

  3. The mTOR effectors 4EBP1 and S6K2 are frequently coexpressed, and associated with a poor prognosis and endocrine resistance in breast cancer.

  4. The p85 S6K1 (show RPS6KB1 Proteins) promotes H2O2-induced cell death via a rapamycin-insensitive mechanism.

  5. S6K2 amplification was frequently observed in gastric cancer and was related to a poor prognosis

  6. S6K1 and S6K2 gene amplification was associated with a worse prognosis.

  7. S6K2 expression dictates tissue-specific requirement for S6K1 (show RPS6KB1 Proteins) in mediating aberrant mTORC1 signaling and tumorigenesis

  8. Study shows that the two homologues of S6K (show RPS6KB1 Proteins) have distinct effects on Akt (show AKT1 Proteins) activation and cell survivalin breast cancer.

  9. Data show that genetic variation in RPS6KA1 (show RPS6KA1 Proteins), RPS6KA2 (show RPS6KA2 Proteins), and PRS6KB2 were associated with risk of developing colon cancer while only genetic variation in RPS6KA2 (show RPS6KA2 Proteins) was associated with altering risk of rectal cancer.

  10. heterogeneous ribonucleoprotein F (show HNRNPF Proteins) is involved in the regulation of cell proliferation via the mammalian target of rapamycin (show FRAP1 Proteins)/S6 kinase 2 pathway

Mouse (Murine) Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 2 (RPS6KB2) interaction partners

  1. S6K2 regulates hepatic energy homeostasis by repressing PPARalpha (show PPARA Proteins) activity.

  2. metabolic functions of S6K (show RPS6KB1 Proteins) in vivo play a key role as a molecular interface connecting dietary lipids to the endogenous control of energy metabolism.

  3. S6K2 expression dictates tissue-specific requirement for S6K1 (show RPS6KB1 Proteins) in mediating aberrant mTORC1 signaling and tumorigenesis

  4. Data show that the absence of ribosomal protein S6 (show RPS6 Proteins) kinases 1 and 2 (S6K1 (show RPS6KB1 Proteins) and S6K2) profoundly impairs animal viability but does not seem to affect the proliferative responses of cells derived from the distinct S6K (show RPS6KB1 Proteins) genotypes.

  5. S6K2 is activated by IL-3 (show Il3 Proteins) in the IL-3 (show Il3 Proteins)-dependent Ba/F3 cell line and this is mediated by mTOR (show FRAP1 Proteins) and its upstream activator PI-3K but not by MAPK (show MAPK1 Proteins) signal pathways.

  6. parallel increase in p70S6K (show RPS6KB1 Proteins) activation and tau phosphorylation could be demonstrated by treating wild-type N2a cells with Abeta25-35

  7. mGluR (show GRM8 Proteins)-LTD is associated with PI3K-, mTOR (show FRAP1 Proteins)-, and ERK (show EPHB2 Proteins)-dependent alterations in the phosphorylation of S6 and S6K (show RPS6KB1 Proteins).

RPS6KB2 Protein Profile

Protein Summary

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates the S6 ribosomal protein and eucaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation.

Alternative names and synonyms associated with RPS6KB2

  • ribosomal protein S6 kinase, 70kDa, polypeptide 2 (RPS6KB2)
  • ribosomal protein S6 kinase, polypeptide 2 (Rps6kb2)
  • 70kDa protein
  • KLS protein
  • p70(S6K)-beta protein
  • P70-beta protein
  • P70-beta-1 protein
  • P70-beta-2 protein
  • p70S6Kb protein
  • S6K-beta2 protein
  • S6K2 protein
  • SRK protein
  • STK14B protein

Protein level used designations for RPS6KB2

70 kDa ribosomal protein S6 kinase 2 , P70S6K2 , S6 kinase-related kinase , S6K-beta , S6K-beta-2 , p70 S6 kinase beta , p70 S6K-beta , p70 S6KB , p70 ribosomal S6 kinase beta , p70-S6K 2 , ribosomal protein S6 kinase beta-2 , serine/threonine-protein kinase 14 beta , serine/threonine-protein kinase 14B , ribosomal protein S6 kinase, 70kDa, polypeptide 2 , S6 kinase 2 , ribosomal protein S6 kinase, 70kD, polypeptide 2

GENE ID SPECIES
6199 Homo sapiens
361696 Rattus norvegicus
58988 Mus musculus
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