Browse our anti-SKI-Like Oncogene (SKIL) Antibodies

Full name:
anti-SKI-Like Oncogene Antibodies (SKIL)
On www.antibodies-online.com are 94 SKI-Like Oncogene (SKIL) Antibodies from 21 different suppliers available. Additionally we are shipping SKI-Like Oncogene Proteins (4) and SKI-Like Oncogene Kits (3) and many more products for this protein. A total of 110 SKI-Like Oncogene products are currently listed.
Synonyms:
DKFZp459L122, SKIL, Skir, Sno, SnoA, SnoI, SnoN
list all antibodies Gene Name GeneID UniProt
SKIL 20482 Q60665
SKIL 6498 P12757
SKIL 114208  

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Most Popular Reactivities for anti-SKI-Like Oncogene (SKIL) Antibodies

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Top referenced anti-SKI-Like Oncogene Antibodies

  1. Cow (Bovine) Polyclonal SKIL Primary Antibody for WB - ABIN2779596 : Pearson-White, Crittenden: Proto-oncogene Sno expression, alternative isoforms and immediate early serum response. in Nucleic acids research 1997 (PubMed)

More Antibodies against SKI-Like Oncogene Interaction Partners

Mouse (Murine) SKI-Like Oncogene (SKIL) interaction partners

  1. Loss of SnoN is associated with partial embryonic lethality, mostly due to defects in angiogenesis in both the yolk sac (show ADCY10 Antibodies) and embryo body

  2. SnoN mediates a negative feedback mechanism evoked by TGF-beta to inhibit BMP signaling and, subsequently, hypertrophic maturation of chondrocytes.

  3. SnoN, a negative regulator of TGF-beta (show TGFB1 Antibodies) signaling, coordinates TGF-beta (show TGFB1 Antibodies) and prolactin (show PRL Antibodies) signaling to control alveologenesis and lactogenesis.

  4. mRNA for positive regulators of Fshb (show FSHB Antibodies) expression, such as Fos and Jun (show JUN Antibodies), were up-regulated at slower pulse frequencies than a number of potential negative regulators, such as the corepressors Skil, Crem (show CREM Antibodies), and Tgif1 (show TGIF1 Antibodies).

  5. The endogenous SnoN plays a role in regulating ADAM12 (show ADAM12 Antibodies) expression in response to TGFbeta1 (show TGFB1 Antibodies).

  6. The authors conclude that somatic and germ cells at all differentiation stages are actively transducing TGFbeta (show TGFB1 Antibodies) superfamily signals but that responses to these ligands may be selectively modulated by SnoN2.

  7. Sno is a significant negative regulator of antiproliferative TGF-beta (show TGFB1 Antibodies) signaling in both T cells and other cell types in vivo

  8. SnoN is directly regulated by sumoylation leading to the enhancement of the ability of SnoN to repress transcription in a promoter-specific manner

  9. SnoN plays both pro-tumorigenic and antitumorigenic roles at different stages of mammalian malignant progression

  10. Arkadia (show RNF111 Antibodies) induces degradation of SnoN and c-Ski (show SKI Antibodies) in addition to Smad7 (show SMAD7 Antibodies).

Human SKI-Like Oncogene (SKIL) interaction partners

  1. signal transducer and activator of transcription (Stat (show STAT1 Antibodies))3 (show STAT3 Antibodies) represses Smad3 (show SMAD3 Antibodies) in synergy with the potent negative regulators of TGF-beta (show TGFB1 Antibodies) signaling, c-Ski (show SKI Antibodies) and SnoN, whereby renders gefitinib-sensitive HCC827 cells resistant

  2. SnoN interacts with multiple components of the Hippo pathway to inhibit the binding of Lats2 (show LATS2 Antibodies) to TAZ (show TAZ Antibodies) and the subsequent phosphorylation of TAZ (show TAZ Antibodies), leading to TAZ (show TAZ Antibodies) stabilization.

  3. suggest that SnoN suppresses TGF-betainduced epithelial-mesenchymal transition and invasion of bladder cancer cells in a TIF1gammadependent manner

  4. the findings of this study demonstrate that the downregulation of SnoN expression in hRPTECs under high-glucose conditions is mediated by the increased expression of Smurf2 (show SMURF2 Antibodies) through the TGF-b1/Smad (show SMAD1 Antibodies) signaling pathway.

  5. RNAi-mediated downregulation of SnoN effectively inhibited proliferation and enhanced apoptosis of pancreatic cells.

  6. SKIL knockdown led to growth arrest in PC-3 (show PCSK1 Antibodies) and LNCaP cell line models of prostate cancer, and its overexpression led to increased invasiveness in RWPE-1 cells.

  7. Whole exome sequencing of the blood of the patient and both parents revealed a de novo germline SKIL mutation in the child that was not present in either parent

  8. Data indicate that tripartite motif containing 33 (show TRIM33 Antibodies) protein TIF1gamma (show TRIM33 Antibodies) promotes sumoylation of SKI-like proto-oncogene (show RAB1A Antibodies) protein SnoN1 and regulates epithelial-mesenchymal transition (EMT (show ITK Antibodies)).

  9. The results indicate that protein ubiquitination promotes megakaryopoiesis via degrading SnoN, an inhibitor of CD61 (show ITGB3 Antibodies) expression, strengths the roles of ubiquitination in cellular differentiation.

  10. SnoNspecific siRNA is capable of effectively inhibiting the expression of SnoN in human HepG2 cells, and the downregulation of SnoN expression induces growth inhibition and apoptosis

SKI-Like Oncogene (SKIL) Antigen Profile

Antigen Summary

The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene.

Alternative names and synonyms associated with SKI-Like Oncogene (SKIL)

  • SKI-like oncogene (SKIL) antibody
  • SKI-like oncogene (skil) antibody
  • SKI-like (Skil) antibody
  • SKI-like oncogene (Skil) antibody
  • DKFZp459L122 antibody
  • SKIL antibody
  • Skir antibody
  • Sno antibody
  • SnoA antibody
  • SnoI antibody
  • SnoN antibody

Protein level used designations for SKIL

SKI-like oncogene , Ski-like protein , ski-like protein-like , ski-like protein , ski-related oncogene , ski/sno related , ski-related oncogene snoN , v-ski sarcoma viral oncogene homolog

GENE ID SPECIES
460844 Pan troglodytes
100010058 Monodelphis domestica
100057606 Equus caballus
100174070 Pongo abelii
100351337 Oryctolagus cuniculus
100395994 Callithrix jacchus
100474292 Ailuropoda melanoleuca
100492636 Xenopus (Silurana) tropicalis
100553902 Anolis carolinensis
100599983 Nomascus leucogenys
20482 Mus musculus
6498 Homo sapiens
488159 Canis lupus familiaris
527910 Bos taurus
114208 Rattus norvegicus
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