TXN2 Protein (AA 60-166) (His tag)
-
- Target See all TXN2 Proteins
- TXN2 (Thioredoxin 2 (TXN2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 60-166
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This TXN2 protein is labelled with His tag.
- Purpose
- Recombinant Human Thioredoxin-2/TXN2 (N-6His)
- Sequence
- MTTFNIQDGP DFQDRVVNSE TPVVVDFHAQ WCGPCKILGP RLEKMVAKQH GKVVMAKVDI DDHTDLAIEY EVSAVPTVLA MKNGDVVDKF VGIKDEDQLE AFLKKLIG
- Characteristics
- Recombinant Human Thioredoxin-2/TXN2 is produced with our E. coli expression system. The target protein is expressed with sequence (Thr60-Gly166) of Human TXN2.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product TXN2 Protein
-
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
-
It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- 4 °C/-20 °C/-80 °C
- Storage Comment
-
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. - Expiry Date
- 3 months
-
- Target
- TXN2 (Thioredoxin 2 (TXN2))
- Alternative Name
- Thioredoxin-2/Trx-2/MTRX (TXN2 Products)
- Synonyms
- MT-TRX Protein, MTRX Protein, TRX2 Protein, 31884 Protein, CG31884 Protein, CG3864 Protein, DTrx-2 Protein, DmTrx-2 Protein, DmelTrx-2 Protein, Dmel\\CG31884 Protein, Trx Protein, anon-WO0118547.188 Protein, dmtrx-2 Protein, 2510006J11Rik Protein, AI788873 Protein, Trx2 Protein, zgc:77127 Protein, thioredoxin 2 Protein, thioredoxin-2 Protein, thiol reductase thioredoxin Protein, thioredoxin 2 L homeolog Protein, TXN2 Protein, Trx-2 Protein, LOC409451 Protein, VPA0972 Protein, VS_RS18125 Protein, VCD_000568 Protein, VEA_000083 Protein, trx2 Protein, Txn2 Protein, txn2 Protein, txn2.L Protein
- Background
-
Thioredoxin-2 (TXN2) is a mitochondrial member of the thioredoxin family. Thioredoxin-2 is extensively expressed in adult and fetal tissues. Thioredoxin-2 contains an N-terminal 59 amino acid transit peptide, which is cleaved before translocating to mitochondria. Mitochondrial thioredoxin play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis. Thioredoxin-2 could be involved in the resistance to anti-tumor agents and possesses a dithiol-reducing activity. In addition, Thioredoxin-2 is important at low oxidative stress conditions.
Alternative Names: Thioredoxin Mitochondrial, MTRX, Mt-Trx, Thioredoxin-2, TXN2, TRX2 - Molecular Weight
- 12 kDa
- UniProt
- Q99757
- Pathways
- Cell RedoxHomeostasis
-