MEK2 Protein (His tag)
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- Target See all MEK2 (MAP2K2) Proteins
- MEK2 (MAP2K2) (Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This MEK2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product MAP2K2 Protein
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Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) (AA 1-400) (Active) protein (GST tag)
MAP2K2 Origin: Human Host: Insect cells (Sf21) Recombinant SDS, Func Active
Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) proteinMAP2K2 Origin: Human, Mouse, Rat Host: Insect cells (Sf9) Recombinant WB
Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) (AA 1-400) protein (His tag)MAP2K2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) (AA 1-400) protein (GST tag)MAP2K2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) (AA 291-400) protein (GST tag)MAP2K2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) (AA 1-360) protein (GST tag)MAP2K2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) (AA 1-400) protein (Strep Tag)Crystallography grade MAP2K2 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) (AA 1-401) protein (Strep Tag)Crystallography grade MAP2K2 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
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- Comment
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Synonyms: Dual specificity mitogen-activated protein kinase kinase 2, MAPKK2, MEK2, MKK2, PRKMK2
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.1 M NaCl, 10% glycerol
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- MEK2 (MAP2K2) (Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2))
- Alternative Name
- MAP2K2 (MAP2K2 Products)
- Synonyms
- CFC4 Protein, MAPKK2 Protein, MEK2 Protein, MKK2 Protein, PRKMK2 Protein, AA589381 Protein, MK2 Protein, Prkmk2 Protein, ATMKK2 Protein, F27B13.50 Protein, F27B13_50 Protein, MAP KINASE KINASE 1 Protein, MAP kinase kinase 2 Protein, MK1 Protein, map2k2 Protein, wu:fa56c06 Protein, zgc:123171 Protein, zgc:172250 Protein, mitogen-activated protein kinase kinase 2 Protein, mitogen activated protein kinase kinase 2 Protein, MAP kinase kinase 2 Protein, mitogen-activated protein kinase kinase 2a Protein, mitogen-activated protein kinase kinase 2b Protein, MAP2K2 Protein, Map2k2 Protein, MKK2 Protein, map2k2a Protein, map2k2b Protein
- Background
- MAP2K2, also known as MEK2, belongs to the STE grouping of kinases. Both MEK2 and the related MEK1 are dualspecificity kinases, phosphorylating and activating the mitogen-activated protein kinases ERK1 and ERK2 at T and Y positions within the phosphoacceptor sequence T-E-Y. MAP2K2 is activated by a wide variety of growth factors and cytokines and also by membrane depolarization and calcium influx. Recombinant human MAP2K2 proetin, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 46.9 kDa (424aa), confirmed by MALDI-TOF
- NCBI Accession
- NP_109587
- Pathways
- MAPK Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling
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