EIF4H Protein (His tag)
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- Target See all EIF4H Proteins
- EIF4H (Eukaryotic Translation Initiation Factor 4H (EIF4H))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This EIF4H protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product EIF4H Protein
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- Comment
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Synonyms: Eukaryotic translation initiation factor 4H, eIF-4H, WBSCR1, WSCR1
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.2 M NaCl, 50% glycerol, 2 mM DTT
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- EIF4H (Eukaryotic Translation Initiation Factor 4H (EIF4H))
- Alternative Name
- EIF4H (EIF4H Products)
- Synonyms
- wscr1 Protein, wbscr1 Protein, WBSCR1 Protein, Wbscr1 Protein, WSCR1 Protein, eIF-4H Protein, AU018978 Protein, D5Ertd355e Protein, E430026L18Rik Protein, Ef4h Protein, Wscr1 Protein, mKIAA0038 Protein, zgc:77282 Protein, eukaryotic translation initiation factor 4H Protein, eukaryotic translation initiation factor 4H L homeolog Protein, eukaryotic translation initiation factor 4h Protein, transaltion initiation factor Protein, Eukaryotic translation initiation factor 4H Protein, eif4h Protein, eif4h.L Protein, EIF4H Protein, Eif4h Protein, LOC733087 Protein, SJAG_03433 Protein, MGYG_07815 Protein, Tsp_06589 Protein, if4h Protein
- Background
- Eukaryotic translation initiation factor 4H, also known as EIF4H, is a 248 amino acid protein that localizes to the perinuclear region of the cytoplasm and is expressed as two isoforms, designated short and long. EIF4H induces the RNA-dependent ATP hydrolysis catalyzed by the initiation factors EIF4A and EIF4B. EIF4H was further shown to stimulate the initial rate and extent of EIF4A-mediated mRNA secondary structure unwinding. Defects in the gene encoding EIF4H are associated with Williams- Beuren syndrome (WBS), a rare developmental disorder characterized by cardiovascular and musculo-skeletal abnormalities. Recombinant human EIF4H protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 29.9 kDa (272aa), confirmed by MALDI-TOF
- NCBI Accession
- NP_071496
- Pathways
- SARS-CoV-2 Protein Interactome
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