HBXIP Protein (His tag)
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- Target See all HBXIP Proteins
- HBXIP (Hepatitis B Virus X-Interacting Protein (HBXIP))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This HBXIP protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product HBXIP Protein
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- Comment
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Synonyms: Hepatitis B virus x interacting protein, XIP
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.1 M NaCl, 10% glycerol,1 MM EDTA
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- HBXIP (Hepatitis B Virus X-Interacting Protein (HBXIP))
- Alternative Name
- HBXIP (HBXIP Products)
- Synonyms
- HBXIP Protein, xip Protein, XIP Protein, 1110003H18Rik Protein, Hbxip Protein, late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 Protein, Hepatitis B virus X-interacting protein Protein, LAMTOR5 Protein, xip Protein, Lamtor5 Protein
- Target Type
- Viral Protein
- Background
- Hepatitis B virus x interacting protein, also known as HBXIP, was originally identified by its ability to form a complex with the C-terminus of hepatitis B virus X (HBX) protein. HBXIP negatively regulates the activity of HBX and alters the replicative life cycle of the virus. In addition, HBXIP is involved in bipolar spindle formation and regulates centrosome dynamics and cytokinesis in cells, possibly through an interaction with Dynein light chain. Recombinant human HBXIP protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 20.7 kDa (197aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_006393
- Pathways
- PI3K-Akt Signaling, Regulation of Cell Size
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