Smooth Muscle Actin Protein (His tag)
-
- Target See all Smooth Muscle Actin (ACTA2) Proteins
- Smooth Muscle Actin (ACTA2) (Actin, alpha 2, Smooth Muscle, Aorta (ACTA2))
- Protein Type
- Recombinant
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Smooth Muscle Actin protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product ACTA2 Protein
-
-
- Comment
-
Synonyms: Actin, aortic smooth muscle, AAT6, ACTSA, MYMY5
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 10% glycerol
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
-
- Target
- Smooth Muscle Actin (ACTA2) (Actin, alpha 2, Smooth Muscle, Aorta (ACTA2))
- Alternative Name
- ACTA2 (ACTA2 Products)
- Synonyms
- AAT6 Protein, ACTSA Protein, MYMY5 Protein, GAMMA-ACTIN Protein, ACT Protein, ACTA3 Protein, ACTE Protein, ACTL3 Protein, ACTSG Protein, Act-4 Protein, Act4 Protein, SMGA Protein, 0610041G09Rik Protein, Actvs Protein, SMalphaA Protein, a-SMA Protein, alphaSMA Protein, wu:fb63d03 Protein, ASMA Protein, SMactin Protein, a-sma Protein, aat6 Protein, actsa Protein, mymy5 Protein, sm-actin Protein, ACTA2 Protein, actc1 Protein, ACT-4 Protein, asma Protein, ACTGE Protein, actin, alpha 2, smooth muscle, aorta Protein, actin, gamma 2, smooth muscle, enteric Protein, actin, alpha 2, smooth muscle, aorta L homeolog Protein, ACTA2 Protein, ACTG2 Protein, Actg2 Protein, Acta2 Protein, acta2 Protein, acta2.L Protein
- Background
- ACTA2 belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified. Recombinant human ACTA2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 44.4 kDa (400aa), confirmed by MALDI-TOF
- NCBI Accession
- NP_001604
- Pathways
- Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development
-