Cytohesin 2 Protein (CYTH2) (His tag)
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- Target See all Cytohesin 2 (CYTH2) Proteins
- Cytohesin 2 (CYTH2)
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Cytohesin 2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product CYTH2 Protein
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- Comment
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Synonyms: Cytohesin 2, ARNO, CTS18, CTS18.1, PSCD2, PSCD2L, SEC7L, Sec7p-L, Sec7p-like
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.2 M NaCl, 10% glycerol,1 MM DTT
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- Cytohesin 2 (CYTH2)
- Alternative Name
- CYTH2 (CYTH2 Products)
- Synonyms
- ARNO Protein, CTS18 Protein, CTS18.1 Protein, PSCD2 Protein, PSCD2L Protein, SEC7L Protein, Sec7p-L Protein, Sec7p-like Protein, CLM2 Protein, Pscd2 Protein, Arno Protein, Sec7 Protein, Sec7B Protein, pscd2 Protein, MGC84366 Protein, CYTH2 Protein, cyth2 Protein, cytohesin 2 Protein, cytohesin-2 Protein, cytohesin 2 L homeolog Protein, si:dkey-283b15.4 Protein, CYTH2 Protein, PTRG_08834 Protein, Cyth2 Protein, cyth2.L Protein, cyth2 Protein, si:dkey-283b15.4 Protein
- Background
- CYTH2, also known as Cytohesin-2 and ARNO, is an ARF-1 guanine nucleotide exchange factor (GEF). ARF (ADP ribosylation factor) proteins, a group within the RAS superfamily, are GTP-binding proteins central to the process of vesicle budding. This protein promotes guanine-nucleotide exchange on ARF1, ARF3 and ARF6. Also it promotes the activation of ARF factors through replacement of GDP with GTP. The cell membrane form, in association with ARL4 proteins, recruits ARF6 to the plasma membrane. Recombinant human CYTH2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 48.9 kDa (422aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_004219
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