RAP2B Protein (His tag)
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- Target See all RAP2B Proteins
- RAP2B (RAP2B, Member of RAS Oncogene Family (RAP2B))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This RAP2B protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product RAP2B Protein
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- Comment
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Synonyms: Ras-related protein Rap-2b, RAP2B, member of RAS oncogene family
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 20% glycerol, 1 MM DTT
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- RAP2B (RAP2B, Member of RAS Oncogene Family (RAP2B))
- Alternative Name
- RAP2B (RAP2B Products)
- Synonyms
- Rap2b Protein, wu:fi34c06 Protein, zgc:55550 Protein, RAP2B Protein, LOC100223676 Protein, 4021402C18Rik Protein, AA408554 Protein, RAP2B, member of RAS oncogene family S homeolog Protein, RAP2B, member of RAS oncogene family Protein, RAS-like, family 10, member A Protein, GTP-binding protein Rhes pseudogene Protein, rap2b.S Protein, rap2b Protein, RASL10A Protein, RAP2B Protein, LOC100223676 Protein, Rap2b Protein
- Background
- Ras-related protein Rap-2b, also known as RAP2B, belongs to a family of RAS-related genes. Unlike normal ras proteins that have a nontransforming glutamine residue at aa 61, Rap2B has a threonine residue in that position. This change makes the intrinsic GTPase activity for Rap2B lower, thereby allowing it to exist in the activated state for a longer period of time than normal ras proteins. RAP2B is a platelet protein that is activated by thrombin and involved in platelet activation. RAP2B may be a novel candidate oncogene that plays important roles in carcinogenesis through activation of NF-kappaB pathway. Recombinant human RAP2B protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 22.9kDa (206aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_002877
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