HAX1 Protein (His tag)
-
- Target See all HAX1 Proteins
- HAX1 (HCLS1 Associated Protein X-1 (HAX1))
- Protein Type
- Recombinant
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This HAX1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 80 % by SDS - PAGE
- Top Product
- Discover our top product HAX1 Protein
-
-
- Comment
-
Synonyms: HCLS1 associated protein X-1 isoform a, HCLSBP1, HS1BP1, SCN3
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.1 M NaCl
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
-
- Target
- HAX1 (HCLS1 Associated Protein X-1 (HAX1))
- Alternative Name
- HAX1 (HAX1 Products)
- Synonyms
- HAX1 Protein, hax1 Protein, HCLSBP1 Protein, HS1BP1 Protein, SCN3 Protein, HAX-1 Protein, Hs1bp1 Protein, HSP1BP-1 Protein, SIG-111 Protein, Silg111 Protein, mHAX-1s Protein, HCLS1 associated protein X-1 Protein, HCLS1 associated X-1 Protein, HAX1 Protein, hax1 Protein, Hax1 Protein
- Background
- HAX1 is known to associate with HS1, a substrate of Src family tyrosine kinases. It also interacts with the product of PKD2, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with F-actin-binding protein, cortactin. It is associated with autosomal recessive severe congenital neutropenia, also known as Kostmann syndrome. Recombinant human HAX1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 33.7 kDa(299aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_006109
- Pathways
- Regulation of Actin Filament Polymerization
-