CD46 Protein (CD46) (His tag)
-
- Target See all CD46 Proteins
- CD46
- Protein Type
- Recombinant
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This CD46 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product CD46 Protein
-
CD46 (CD46) (AA 35-343) protein (His tag)
CD46 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD46 (CD46) (AA 35-329) protein (His tag)CD46 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD46 (CD46) (AA 45-344) protein (His tag)CD46 Origin: Dog Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD46 (CD46) (AA 35-313) protein (His tag)CD46 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
CD46 (CD46) (AA 1-384) protein (GST tag)CD46 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
CD46 (CD46) (AA 36-135) protein (GST tag)CD46 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
-
- Comment
-
Synonyms: Membrane cofactor protein isoform 14, AHUS2, MCP, MIC10, TLX, TRA2.10
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.1 M NaCl, 20% glycerol
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
-
- Target
- CD46
- Alternative Name
- CD46 (CD46 Products)
- Synonyms
- AHUS2 Protein, MCP Protein, MIC10 Protein, TLX Protein, TRA2.10 Protein, Mcp Protein, CD46 Protein, CD46 molecule Protein, CD46 antigen, complement regulatory protein Protein, CD46 molecule, complement regulatory protein Protein, membrane cofactor protein-like Protein, CD46 Protein, Cd46 Protein, LOC100341359 Protein, LOC103789310 Protein
- Background
- Membrane cofactor protein isoform 14, also known as CD46, is a type I membrane protein that has cofactor activity for inactivation of complement components C3b and C4b by serum factor I. This function resides in the complement control protein repeats (CCPs), with CCP1–4 essential for regulation. CD46 is widely distributed on thymocytes, T cells, B cells, monocytes, granulocytes, NK cells, platelets, endothelial cells, epithelial cells, fibroblasts, placenta and sperm, but not on erythrocyte. Recombinant human CD46 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 33.8 kDa (302aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_758860
- Pathways
- Regulation of Actin Filament Polymerization
-
