SOSTDC1 Protein (His tag)
-
- Target See all SOSTDC1 Proteins
- SOSTDC1 (Sclerostin Domain Containing 1 (SOSTDC1))
- Protein Type
- Recombinant
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This SOSTDC1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product SOSTDC1 Protein
-
-
- Comment
-
Synonyms: Sclerostin domain-containing protein 1, CDA019, ECTODIN, USAG1
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea, 10% glycerol
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
-
- Target
- SOSTDC1 (Sclerostin Domain Containing 1 (SOSTDC1))
- Alternative Name
- SOSTDC1 (SOSTDC1 Products)
- Synonyms
- SOSTDC1 Protein, zgc:110293 Protein, DKFZp469J0531 Protein, Usag1 Protein, ECTODIN Protein, USAG1 Protein, 0610006G05Rik Protein, Sostl Protein, USAG-1 Protein, Wise Protein, ectodin Protein, WISE Protein, sclerostin domain containing 1 Protein, sclerostin domain containing 1a Protein, SOSTDC1 Protein, sostdc1a Protein, Sostdc1 Protein
- Background
- SOSTDC1 is a member of the sclerostin family and an N-glycosylated, secreted protein with a C-terminal cystine knot-like domain. This protein functions as a bone morphogenetic protein (BMP) antagonist. Specifically, it directly associates with BMPs, prohibiting them from binding their receptors, thereby regulating BMP signaling during cellular proliferation, differentiation, and programmed cell death. Recombinant human SOSTDC1 protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molecular Weight
- 23kDa (206aa)
- NCBI Accession
- NP_056279
-