SOSTDC1 Protein (Fc Tag)
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- Target See all SOSTDC1 Proteins
- SOSTDC1 (Sclerostin Domain Containing 1 (SOSTDC1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This SOSTDC1 protein is labelled with Fc Tag.
- Purpose
- Human USAG-1 Protein, Fc Tag
- Sequence
- Phe 24 - Ser 206
- Characteristics
- Human USAG-1, Fc Tag (US1-H5254) is expressed from human 293 cells (HEK293). It contains AA Phe 24 - Ser 206 (Accession # Q6X4U4-1).
- Purity
- >90 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product SOSTDC1 Protein
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Sclerostin Domain Containing 1 (SOSTDC1) (AA 1-206) protein (GST tag)
SOSTDC1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Sclerostin Domain Containing 1 (SOSTDC1) (AA 24-206) protein (His tag)Crystallography grade SOSTDC1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Sclerostin Domain Containing 1 (SOSTDC1) (AA 24-206) protein (His tag)Crystallography grade SOSTDC1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Sclerostin Domain Containing 1 (SOSTDC1) (AA 24-206) protein (GST tag)SOSTDC1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Sclerostin Domain Containing 1 (SOSTDC1) proteinSOSTDC1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, ELISA, IP
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- Application Notes
- This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 47.2 kDa. The protein migrates as 45-65 kDa under reducing (R) condition due to glycosylation.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- 51 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5
- Storage
- -20 °C
- Storage Comment
- -20°C
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- Target
- SOSTDC1 (Sclerostin Domain Containing 1 (SOSTDC1))
- Alternative Name
- USAG-1 (SOSTDC1 Products)
- Synonyms
- SOSTDC1 Protein, zgc:110293 Protein, DKFZp469J0531 Protein, Usag1 Protein, ECTODIN Protein, USAG1 Protein, 0610006G05Rik Protein, Sostl Protein, USAG-1 Protein, Wise Protein, ectodin Protein, WISE Protein, sclerostin domain containing 1 Protein, sclerostin domain containing 1a Protein, SOSTDC1 Protein, sostdc1a Protein, Sostdc1 Protein
- Background
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Synonyms: Uterine sensitization-associated gene 1 protein,
Description: USAG1 (uterine sensitization associated gene 1), also known asSOSTDC1 (sclerostin domain-containing 1), Ectodin, is a secreted protein with a glycosylated N-terminus that contains a C-terminal cysteine knot domain. This C-terminal cysteine knot domain is present in numerous growth factors, including TGFβ, NGF, PDGF, vWF, NDP, and mucin-2, and involved in dimerization, receptor binding, and signal transduction. SOSTDC1 negatively regulates BMP signaling during cellular proliferation, differentiation, and apoptosis in several biological processes (such as dentary morphogenesis, embryo implantation in the endo-metrium, and healing of bone fractures) [8]. In addition, SOSTDC1 might also involve cancer development processes through the regulation of the Wnt pathway. - Molecular Weight
- 47.2 kDa
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