IGLL1 Protein (His tag)
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- Target See all IGLL1 Proteins
- IGLL1 (Immunoglobulin lambda-Like Polypeptide 1 (IGLL1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This IGLL1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product IGLL1 Protein
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- Comment
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Synonyms: Immunoglobulin lambda-like polypeptide 1, 14.1, AGM2, CD179b, IGL1, IGL5, IGLJ14.1, IGLL, IGO, IGVPB, VPREB2
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M urea, 10% glycerol
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- IGLL1 (Immunoglobulin lambda-Like Polypeptide 1 (IGLL1))
- Alternative Name
- IGLL1 (IGLL1 Products)
- Synonyms
- 14.1 Protein, AGM2 Protein, CD179b Protein, IGL1 Protein, IGL5 Protein, IGLJ14.1 Protein, IGLL Protein, IGO Protein, IGVPB Protein, VPREB2 Protein, IGLV Protein, IGLL1 Protein, MGC151892 Protein, Igll1 Protein, BB139905 Protein, Igl-5 Protein, Igll Protein, Lambda5 Protein, immunoglobulin lambda like polypeptide 1 Protein, immunoglobulin lambda-like polypeptide 1 Protein, IGLL1 Protein, Igll1 Protein
- Background
- The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. IGLL1 is one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. This gene does not undergo rearrangement. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene. Recombinant human IGLL1protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molecular Weight
- 21.5 kDa (199aa)
- NCBI Accession
- NP_064455
- Pathways
- Regulation of Cell Size
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