VHL Protein (AA 1-219) (His tag)

Catalog No. ABIN1634750

Product Details

Target: VHL (Von Hippel-Lindau Tumor Suppressor, E3 Ubiquitin Protein Ligase (VHL))

Protein Type: Recombinant

Protein Characteristics: AA 1-219

Origin: Dog

Source: Yeast

Purification tag / Conjugate: This VHL protein is labelled with His tag.

Application: ELISA

Sequence: MPRKAGSVEE AEAGAEEVGA EEVGPEESGG EESGAEESGP EESDPEEPGA AAEMEAGQPR PVLRSVNSCE PSQVIFCNRS PRVVLPVWLN FDGEPQPYPT LPPGTGRRIH SYRGHLWLFR DAGTYDGLLV NQTELFVPSL NVDGQPIFAN ITLPVYTLKE RCLQVVRSLV KPENYRRLDI VRSLYEDLED HPNVRKDLER LAQEHIENQR MEGETEDFN

Specificity: Canis familiaris (Dog) (Canis lupus familiaris)

Characteristics: Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.

Purity: > 90 %

Application Details

Comment:

The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: 0.2-2 mg/mL

Buffer: Tris-based buffer, 50 % glycerol

Handling Advice: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week

Storage: -20 °C

Storage Comment: Store at -20 °C, for extended storage, conserve at -20 °C or -80 °C.

Target Details

Target: VHL (Von Hippel-Lindau Tumor Suppressor, E3 Ubiquitin Protein Ligase (VHL))

Alternative Name: Von Hippel-Lindau disease tumor suppressor (VHL) (VHL Products)

Synonyms: HRCA1 Protein, RCA1 Protein, VHL1 Protein, pVHL Protein, BcDNA:RH61560 Protein, CG13221 Protein, DVhl Protein, Dmel\\CG13221 Protein, Dvhl Protein, VHL Protein, d-VHL Protein, d-vhl Protein, dVHL Protein, dmVHL Protein, vhl Protein, rca1 Protein, vhl1 Protein, hrca1 Protein, zgc:158722 Protein, Vhlh Protein, von Hippel-Lindau tumor suppressor Protein, von Hippel-Lindau Protein, von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase Protein, von Hippel-Lindau disease tumor suppressor Protein, VHL Protein, Vhl Protein, vhl Protein, CpipJ_CPIJ009992 Protein

Background: Recommended name: Von Hippel-Lindau disease tumor suppressor.
Alternative name(s): pVHL

UniProt: Q5Q9Z2

Pathways: Tube Formation, Signaling Events mediated by VEGFR1 and VEGFR2, Ubiquitin Proteasome Pathway