CA2 Protein (AA 1-260) (His tag)
-
- Target See all CA2 Proteins
- CA2 (Carbonic Anhydrase II (CA2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-260
-
Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CA2 protein is labelled with His tag.
- Sequence
- AA 1-260
- Characteristics
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 30 kDa. The protein migrates as 30 kDa under reducing (R) condition (SDS-PAGE).
- Purity
- >95 % as determined by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product CA2 Protein
-
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Buffer
- 20 mM Tris, 150 mM NaCl, pH 8.0
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
-
-
Dual-Valve and Counter-Flow Surface Plasmon Resonance." in: Analytical chemistry, Vol. 90, Issue 8, pp. 4972-4977, (2019) (PubMed).
: "
-
Dual-Valve and Counter-Flow Surface Plasmon Resonance." in: Analytical chemistry, Vol. 90, Issue 8, pp. 4972-4977, (2019) (PubMed).
-
- Target
- CA2 (Carbonic Anhydrase II (CA2))
- Alternative Name
- Carbonic Anhydrase II (CA2 Products)
- Synonyms
- CG6906 Protein, CT21171 Protein, Dmel\\CG6906 Protein, CA-2 Protein, caII Protein, car2 Protein, ca ii Protein, ca-ii Protein, BETA CA2 Protein, BETA CARBONIC ANHYDRASE 2 Protein, CA18 Protein, CARBONIC ANHYDRASE 18 Protein, CARBONIC ANHYDRASE 2 Protein, T9L3.40 Protein, T9L3_40 Protein, carbonic anhydrase 2 Protein, LOC100135827 Protein, AI131712 Protein, CAII Protein, Ca2 Protein, Car-2 Protein, Ltw-5 Protein, Lvtw-5 Protein, CA-II Protein, CAC Protein, Car2 Protein, CAR3 Protein, Carbonic anhydrase 2 Protein, carbonic anhydrase 2 L homeolog Protein, carbonic anhydrase 2 Protein, carbonic anhydrase 1 Protein, carbonic anhydrase II Protein, carbonic anhydrase, alpha type, periplasmic Protein, CAH2 Protein, ca2.L Protein, ca2 Protein, CA2 Protein, HCAG_04637 Protein, LOC100135827 Protein, LOC100635510 Protein, Car2 Protein, Ca2 Protein, LOC100154873 Protein, LOC101113341 Protein
- Background
- Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes. CAs form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons (or vice versa), a reversible reaction that occurs rather slowly in the absence of a catalyst. One of the functions of the enzyme in animals is to interconvert carbon dioxide and bicarbonate to maintain acid-base balance in blood and other tissues, and to help transport carbon dioxide out of tissues. The active site of most carbonic anhydrases contains a zinc ion. They are, therefore, classified as metalloenzymes. There are at least five distinct CA families (α, β, γ, δ and ε). These families have no significant amino acid sequence similarity and in most cases are thought to be an example of convergent evolution. The α-CAs are found in humans. Carbonic anhydrase II (CA2) is also known as Carbonate dehydratase II, Carbonic anhydrase C, is one of fourteen forms of human α carbonic anhydrases. Defects in this enzyme are associated with osteopetrosis and renal tubular acidosis. Renal carbonic anhydrase allows the reabsorption of sodium ions in the proximal tubule. Carbonic anhydrase II has been shown to interact with Band 3 and Sodium-hydrogen antiporter 1.
- Molecular Weight
- 30.1 kDa
- NCBI Accession
- NP_000058
-