TNFRSF12A Protein (AA 28-79) (Fc Tag)
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- Target See all TNFRSF12A Proteins
- TNFRSF12A (Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 28-79
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This TNFRSF12A protein is labelled with Fc Tag.
- Sequence
- AA 28-79
- Characteristics
- This protein carries a human IgG1 Fc tag at the N-terminus. The protein has a calculated MW of 33 kDa. As a result of glycosylation, the protein migrates as 32-40 kDa under reducing (R) condition, and 65-80 kDa under non-reducing (NR) condition (SDS-PAGE).
- Purity
- >95 % as determined by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product TNFRSF12A Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- 50 mM Tris, 100 mM Glycine, pH 7.5
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
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- Target
- TNFRSF12A (Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A))
- Alternative Name
- TWEAK R (TNFRSF12A Products)
- Synonyms
- CD266 Protein, FN14 Protein, TWEAKR Protein, AI255180 Protein, C87282 Protein, Fn14 Protein, HPIP Protein, TWEAK-R Protein, TweakR Protein, TNF receptor superfamily member 12A Protein, tumor necrosis factor receptor superfamily, member 12a Protein, TNFRSF12A Protein, Tnfrsf12a Protein
- Background
- Tumor necrosis factor receptor superfamily member 12A (TNFRSF12A) is also known as Fibroblast growth factor-inducible immediate-early response protein 14 (FN14 or FGF-inducible 14), Tweak-receptor, CD antigen CD266. TNFRSF12A contains one TNFR-Cys repeat. TNFRSF12A is highly expressed in heart, placenta and kidney. TNFRSF12A is receptor for TNFSF12/TWEAK, and is weak inducer of apoptosis in some cell types. TNFRSF12A / FN14 promotes angiogenesis and the proliferation of endothelial cells.
- Molecular Weight
- 32.5 kDa
- Pathways
- Apoptosis, Regulation of Cell Size
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