LUM Protein (His tag)
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- Target See all LUM Proteins
- LUM (Lumican (LUM))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This LUM protein is labelled with His tag.
- Application
- Western Blotting (WB)
- Purity
- >95 % as determined by reduced SDS-PAGE.
- Top Product
- Discover our top product LUM Protein
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- Application Notes
- This recombinant protein can be used for WB. For research use only.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Storage
- -80 °C,-20 °C
- Storage Comment
- Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
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- Target
- LUM (Lumican (LUM))
- Alternative Name
- Lumican (LUM Products)
- Synonyms
- MGC64527 Protein, zgc:86661 Protein, ldc Protein, slrr2d Protein, DKFZp468L1116 Protein, LDC Protein, SLRR2D Protein, Ldc Protein, lumican Protein, lumican L homeolog Protein, LUM Protein, lum.L Protein, lum Protein, CpipJ_CPIJ010209 Protein, Lum Protein
- Background
- Lumican (LUM) is also known as Keratan sulfate proteoglycan lumican, KSPG lumican,LDC and SLRR2D, which belongs to the small leucine-rich proteoglycan (SLRP) family and SLRP class II subfamily. LUM /Lumican is present in the extracellular matrix of human articular cartilage at all ages, although its abundance is far greater in the adult. In the adult cartilage LUM /Lumican exists predominantly in a glycoprotein form lacking keratan sulfate, whereas the juvenile form of the molecule is a proteoglycan. LUM participates in the maintenance of tissue homeostasis and modulates cellular functions including cell proliferation, migration, and differentiation. The expression of LUM has been correlated to the growth and metastasis of various malignancies.
- Molecular Weight
- 37.5 kDa
- Gene ID
- 176
- NCBI Accession
- NP_002336
- UniProt
- P51884
- Pathways
- Glycosaminoglycan Metabolic Process
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