COASY Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- Target See all COASY Proteins
- COASY (CoA Synthase (COASY))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 2
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This COASY protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human CoA synthase (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product COASY Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- COASY (CoA Synthase (COASY))
- Alternative Name
- Coa Synthase (COASY Products)
- Synonyms
- DPCK Protein, NBP Protein, PPAT Protein, UKR1 Protein, pOV-2 Protein, 1300003G02Rik Protein, Dpck Protein, Ppat Protein, Ukr1 Protein, COASY Protein, zgc:92337 Protein, PPAT/DPCK Protein, Coenzyme A synthase Protein, CoA synthase Protein, bifunctional coenzyme A synthase Protein, Bifunctional coenzyme A synthase Protein, COASY Protein, Coasy Protein, CpipJ_CPIJ008826 Protein, pco122135 Protein, coasy Protein
- Background
- Coenzyme A (CoA) functions as a carrier of acetyl and acyl groups in cells and thus plays an important role in numerous synthetic and degradative metabolic pathways in all organisms. In eukaryotes, CoA and its derivatives are also involved in membrane trafficking and signal transduction. This gene encodes the bifunctional protein coenzyme A synthase (CoAsy) which carries out the last two steps in the biosynthesis of CoA from pantothenic acid (vitamin B5). The phosphopantetheine adenylyltransferase domain of this bifunctional protein catalyzes the conversion of 4'-phosphopantetheine into dephospho-coenzyme A (dpCoA) while its dephospho-CoA kinase domain completes the final step by phosphorylating dpCoA to form CoA. Mutations in this gene are associated with neurodegeneration with brain iron accumulation (NBIA). Alternative splicing results in multiple isoforms.
- Molecular Weight
- 62.1 kDa
- NCBI Accession
- NP_001035994
- Pathways
- Ribonucleoside Biosynthetic Process
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