MICU1 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2713249

Product Details

Target: MICU1 (Mitochondrial Calcium Uptake 1 (MICU1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This MICU1 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human CBARA1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: MICU1 (Mitochondrial Calcium Uptake 1 (MICU1))

Alternative Name: Cbara1 (MICU1 Products)

Synonyms: CALC Protein, CBARA1 Protein, EFHA3 Protein, C730016L05Rik Protein, Calc Protein, Cbara1 Protein, mitochondrial calcium uptake 1 Protein, MICU1 Protein, Micu1 Protein

Background: This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described.

Molecular Weight: 54.4 kDa

NCBI Accession: NP_006068