ASAH1 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- Target See all ASAH1 Proteins
- ASAH1 (N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 (ASAH1))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 2
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This ASAH1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Acid ceramidase (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product ASAH1 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- ASAH1 (N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 (ASAH1))
- Alternative Name
- Acid Ceramidase (ASAH1 Products)
- Synonyms
- AC Protein, ACDase Protein, ASAH Protein, PHP Protein, PHP32 Protein, SMAPME Protein, 2310081N20Rik Protein, Asah Protein, MGC82286 Protein, asah1 Protein, zgc:101637 Protein, ASAH1 Protein, zgc:66026 Protein, N-acylsphingosine amidohydrolase 1 Protein, N-acylsphingosine amidohydrolase (acid ceramidase) 1 Protein, N-acylsphingosine amidohydrolase (acid ceramidase) 1 L homeolog Protein, N-acylsphingosine amidohydrolase (acid ceramidase) 1a Protein, Acid ceramidase Protein, N-acylsphingosine amidohydrolase (acid ceramidase) 1b Protein, ASAH1 Protein, Asah1 Protein, asah1.L Protein, asah1a Protein, asah-1 Protein, asah1b Protein
- Background
- This gene encodes a member of the acid ceramidase family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. Processing of this preproprotein generates alpha and beta subunits that heterodimerize to form the mature lysosomal enzyme, which catalyzes the degradation of ceramide into sphingosine and free fatty acid. This enzyme is overexpressed in multiple human cancers and may play a role in cancer progression. Mutations in this gene are associated with the lysosomal storage disorder, Farber lipogranulomatosis, and a neuromuscular disorder, spinal muscular atrophy with progressive myoclonic epilepsy.
- Molecular Weight
- 46.3 kDa
- NCBI Accession
- NP_004306
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