ANAPC5 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
-
- Target See all ANAPC5 Proteins
- ANAPC5 (Anaphase Promoting Complex Subunit 5 (ANAPC5))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
-
Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This ANAPC5 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
-
- Recombinant human APC5 / ANAPC5 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product ANAPC5 Protein
-
-
- Application Notes
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
-
The tag is located at the C-terminal.
- Restrictions
- For Research Use only
-
- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
- Target
- ANAPC5 (Anaphase Promoting Complex Subunit 5 (ANAPC5))
- Alternative Name
- Apc5,anapc5 (ANAPC5 Products)
- Synonyms
- APC5 Protein, DDBDRAFT_0206386 Protein, DDBDRAFT_0234269 Protein, DDB_0206386 Protein, DDB_0234269 Protein, zgc:55800 Protein, wu:fb75a09 Protein, ANAPC5 Protein, MGC89697 Protein, 2510006G12Rik Protein, AA408751 Protein, AA536819 Protein, AA986414 Protein, Anpc5 Protein, F12K11.7 Protein, F12K11_7 Protein, anaphase promoting complex subunit 5 Protein, anaphase-promoting complex subunit 5 Protein, anaphase promoting complex subunit 5 L homeolog Protein, anaphase-promoting complex subunit Protein, anaphase-promoting complex subunit Apc5 Protein, ANAPC5 Protein, anapc5 Protein, LOC100093215 Protein, anapc5.L Protein, Anapc5 Protein, AT1G06590 Protein, apc5 Protein
- Background
- This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a.
- Molecular Weight
- 84.9 kDa
- NCBI Accession
- NP_057321
- Pathways
- M Phase
-