ACLY Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all ACLY Proteins
- ACLY (ATP Citrate Lyase (ACLY))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This ACLY protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human ATP-citrate synthase (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product ACLY Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- ACLY (ATP Citrate Lyase (ACLY))
- Alternative Name
- Atp-Citrate Synthase (ACLY Products)
- Synonyms
- ACLY Protein, DDBDRAFT_0205389 Protein, DDBDRAFT_0235360 Protein, DDB_0205389 Protein, DDB_0235360 Protein, ACL Protein, BcDNA:LD21334 Protein, CG8322 Protein, DmATPCL Protein, Dmel\\CG8322 Protein, anon-WO0140519.179 Protein, dATPCL Protein, l(2)01466 Protein, l(2)k09217 Protein, n(2)k09217 Protein, ATPCL Protein, CLATP Protein, A730098H14Rik Protein, AW538652 Protein, Clatp Protein, acly Protein, cb722 Protein, zgc:92008 Protein, ATP citrate lyase Protein, ATP citrate lyase S homeolog Protein, ATP-citrate synthase Protein, citrate synthase, mitochondrial Protein, atp-citrate synthase Protein, ATP citrate lyase a Protein, ACLY Protein, acly.S Protein, LOC587157 Protein, acly Protein, ATPCL Protein, LOC5564509 Protein, CpipJ_CPIJ010291 Protein, Bm1_26245 Protein, ACL Protein, Acly Protein, aclya Protein
- Background
- ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
- Molecular Weight
- 120.7 kDa
- NCBI Accession
- NP_001087
- Pathways
- Warburg Effect
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