BACE2 Protein (Transcript Variant A) (Myc-DYKDDDDK Tag)
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- Target See all BACE2 Proteins
- BACE2 (beta-Site APP-Cleaving Enzyme 2 (BACE2))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant A
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This BACE2 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human BACE2 (transcript variant a) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product BACE2 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- BACE2 (beta-Site APP-Cleaving Enzyme 2 (BACE2))
- Alternative Name
- Bace2 (BACE2 Products)
- Synonyms
- AEPLC Protein, ALP56 Protein, ASP1 Protein, ASP21 Protein, BAE2 Protein, CEAP1 Protein, DRAP Protein, 1110059C24Rik Protein, AI850424 Protein, ARP1 Protein, CDA13 Protein, beta-site APP-cleaving enzyme 2 Protein, BACE2 Protein, Bace2 Protein
- Background
- This gene encodes an integral membrane glycoprotein that functions as an aspartic protease. The encoded protein cleaves amyloid precursor protein into amyloid beta peptide, which is a critical step in the etiology of Alzheimer&aposs disease and Down syndrome. The protein precursor is further processed into an active mature peptide. Alternative splicing results in multiple transcript variants.
- Molecular Weight
- 49.8 kDa
- NCBI Accession
- NP_036237
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