BUB1B Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2715361

Product Details

Target: BUB1B (Budding Uninhibited By Benzimidazoles 1 Homolog beta (Yeast) (BUB1B))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This BUB1B protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human BUB1B protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: BUB1B (Budding Uninhibited By Benzimidazoles 1 Homolog beta (Yeast) (BUB1B))

Alternative Name: Bub1b (BUB1B Products)

Synonyms: BUB1beta Protein, BUBR1 Protein, Bub1A Protein, MAD3L Protein, MVA1 Protein, SSK1 Protein, hBUBR1 Protein, AU045529 Protein, bub1b Protein, BUB1 Protein, BUB1-like Protein, BubR1 Protein, BubRI Protein, CG14030 Protein, CG14030/Bub1 Protein, Dmel\\CG14030 Protein, bub1 Protein, BUB1 mitotic checkpoint serine/threonine kinase B Protein, BUB1B, mitotic checkpoint serine/threonine kinase Protein, BUB1B, mitotic checkpoint serine/threonine kinase L homeolog Protein, Mitotic checkpoint serine/threonine-protein kinase BUB1 beta Protein, Bub1 kinase Protein, BUB1B Protein, Bub1b Protein, bub1b.L Protein, bub1b Protein, Bub1 Protein

Background: This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer.

Molecular Weight: 119.3 kDa

NCBI Accession: NP_001202