EIF2AK2 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- Target See all EIF2AK2 Proteins
- EIF2AK2 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 2
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This EIF2AK2 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human EIF2AK2 / PKR (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product EIF2AK2 Protein
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Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2) (AA 1-100) protein (GST tag)
EIF2AK2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2) proteinEIF2AK2 Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, ELISA, IP
Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2) (AA 224-502) (Active) protein (His tag)EIF2AK2 Origin: Human Host: Escherichia coli (E. coli) > 80 % AcA, CC Active
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- EIF2AK2 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2))
- Alternative Name
- Eif2ak2,pkr (EIF2AK2 Products)
- Synonyms
- PKR Protein, pkr Protein, EIF2AK2 Protein, DKFZp469K1934 Protein, EIF2AK1 Protein, PRKR Protein, 2310047A08Rik Protein, 4732414G15Rik Protein, AI467567 Protein, AI747578 Protein, Pkr Protein, Prkr Protein, Tik Protein, eukaryotic translation initiation factor 2 alpha kinase 2 Protein, eukaryotic translation initiation factor 2-alpha kinase 2 Protein, EIF2AK2 Protein, eif2ak2 Protein, Eif2ak2 Protein
- Background
- The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene.
- Molecular Weight
- 61.9 kDa
- NCBI Accession
- NP_001129123
- Pathways
- DNA Damage Repair, ER-Nucleus Signaling, Hepatitis C
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