Ezrin Protein (EZR) (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all Ezrin (EZR) Proteins
- Ezrin (EZR)
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Ezrin protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Ezrin (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product EZR Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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A prospective study of autoantibodies to Ezrin and pancreatic cancer risk." in: Cancer causes & control : CCC, Vol. 27, Issue 6, pp. 831-5, (2016) (PubMed).
: "Are ERM (ezrin/radixin/moesin) proteins targets for autoantibodies in demyelinating neuropathies?" in: Human immunology, Vol. 75, Issue 11, pp. 1089-91, (2015) (PubMed).
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A prospective study of autoantibodies to Ezrin and pancreatic cancer risk." in: Cancer causes & control : CCC, Vol. 27, Issue 6, pp. 831-5, (2016) (PubMed).
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- Target
- Ezrin (EZR)
- Alternative Name
- Ezrin (EZR Products)
- Synonyms
- CVIL Protein, CVL Protein, VIL2 Protein, ezr Protein, vil2 Protein, wu:fc05c03 Protein, wu:fj31d06 Protein, cvil Protein, cvl Protein, Vil2 Protein, AW146364 Protein, R75297 Protein, p81 Protein, ezr.S Protein, ezrin Protein, ezrin b Protein, ezrin L homeolog Protein, EZR Protein, ezrb Protein, ezr Protein, Ezr Protein, ezr.L Protein
- Background
- The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.
- Molecular Weight
- 69.2 kDa
- NCBI Accession
- NP_003370
- Pathways
- Maintenance of Protein Location
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