GCKR Protein (Myc-DYKDDDDK Tag)
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- Target See all GCKR Proteins
- GCKR (Glucokinase (Hexokinase 4) Regulator (GCKR))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This GCKR protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human GCKR protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product GCKR Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- GCKR (Glucokinase (Hexokinase 4) Regulator (GCKR))
- Alternative Name
- Gckr (GCKR Products)
- Synonyms
- FGQTL5 Protein, GKRP Protein, GLRE Protein, gckr Protein, glucokinase regulator Protein, glucokinase regulatory protein Protein, glucokinase regulator L homeolog Protein, GCKR Protein, Gckr Protein, gckr.L Protein
- Background
- This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY).
- Molecular Weight
- 68.5 kDa
- NCBI Accession
- NP_001477
- Pathways
- Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus
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